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埃索美拉唑结合黛力新治疗非糜烂性反流病伴抑郁、焦虑患者的临床价值 被引量:2

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摘要 目的了解质子泵抑制剂埃索美拉唑结合黛力新治疗非糜烂性反流病(NERD)的临床价值。方法 110例非糜烂性反流病伴抑郁、焦虑患者随机分为2组,A组56例,给予埃索美拉唑20 mg,早、晚餐前各1次,黛力新10.5 mg,早餐后1次;B组54例,给予埃索美拉唑20 mg,早、中餐前各1次,两组疗程均为6周,疗程结束后通过症状记分进行判断疗效。结果治疗6周后,两组患者的烧心、胸痛、反酸等主要症状的积分分别比较,差异均有统计学意义(P<0.05);A组与B组显效率(83.9%,66.6%)和总有效率(96.6%,81.5%)分别比较,差异均有统计学意义(P<0.05)。结论埃索美拉唑结合黛力新治疗NERD伴抑郁、焦虑的患者是有效的治疗方案之一。
出处 《中国现代药物应用》 2014年第3期157-158,共2页 Chinese Journal of Modern Drug Application
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  • 1Fass R.Epidemiology and pathophysiology of symptomatic gastroesophageal reflux disease.Am J Gastroenterol 2003; 98(Suppl):S2-S7.
  • 2Damiano A,Siddique R,Xu X,Johanson J,Sloan S.Reductions in symptom distress reported by patients with moderately severe,nonerosive gastroesophageal reflux disease treated with rabevrazole.Dig Dis Sci 2003:44:657-662.
  • 3Holtmann G.Reflux disease:the disorder of the third millennium.Eur J Gastroenterol Hepatol 2001;13:S5-11.
  • 4Ho KY,Kang JY,Seow A.Prevalence of gastrointestinal symptoms in a multiracial Asian population,with particular reference to reflux-type symptoms.Am J Gastroenterol 1998;93:1816-1822.
  • 5Wong WM,Lai KC,Lam KF,Hui WM,Hu WH,Lam CL,Xia HH,Huang JQ,Chan CK, Lam SK,Wong BC.Prevalence,clinical spectrum and health care utilization of gastro-oesophageal reflux disease in a Chinese population:a population-based study.Aliment Pharmacol Ther 2003;18:595-604.
  • 6Martinez SD,Malagon IB,Garewal HS,Cui H,Fass R.Nonerosive reflux disease (NERD)-acid reflux and symptom patterns.Aliment Pharmacol Ther 2003;17:537-545.
  • 7Goh KL,Chang CS,Fock KM,Ke M,Park HJ,Lam SK.Gastrooesophageal reflux disease in Asia.J Gastroenterol Hepatol 2000;15:230-238.
  • 8Fock KM,Talley N,Hunt R,Fass R,Nandurkar S,Lam SK,Goh KL,Sollano J. Report of the Asia-Pacific Consensus on the management of gastroesophageal reflux disease.J Gastroenterol Hepatol 2004; 19:357-367.
  • 9Holtmann G,Bytzer P,Metz M,Loeffler V,Blum AL.A randomized, double-blind,comparative study of standarddose rabeprazole and high-dose omeprazole in in gastro-oesophageal reflux disease. Aliment Pharmacol Ther 2002;16:479-485.
  • 10Galmiche JP,Zerbib F,Ducrotte P,Fournet J,Rampal P,Avasthy N, Humphries TJ.Decreasing oesophageal acid exposure patients with GERD:a comparison of rabeprazole and omeprazole.Aliment Pharmacol Ther 2001;15:1343-1350.

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