摘要
目的探讨慢性肾功能衰竭患者治疗中高通量血液透析的临床效果。方法对我院长期接受血液透析的慢性肾功能衰竭患者82例,随机分为两组各41例,研究组采用高通量血液透析治疗,常规组采用低通量血液透析治疗,两组均治疗6个月,观察两组血肌酐、血尿素氮、血红蛋白等指标,治疗期间不良反应及治疗后患者临床症状。结果研究组治疗后与治疗前对比,各项指标均优于治疗前,P<0.05;且Scr、BUN、β2-MG、iPTH均较常规治疗治疗后优越,P<0.05;研究组治疗后除精神异常外其他各项症状发生率均优于常规组,P<0.05;不良反应发生率明显低于常规组,P<0.05。结论高通量血液透析治疗后临床症状明显好转,且可有效清除中、大分子量物资,减低炎性反应等,优于低通量血液透析,值得推广。
Objective Development of high flux hemodialysis treatment on patients with chronic renal failure clinical effect. Methods Long-term receiving hemodialysis in our hospital 82 cases of chronic renal failure patients, 41 cases were randomly divided into two group, use high flux hemodialysis treatment group, conventional group with low flux hemodialysis treatment, two groups were treated for 6 months, observe two groups of serum creatinine, blood urea nitrogen, indices such as hemoglobin,clinical symptoms of patients with adverse reactions during and after treatment. Results Group after treatment compared with before treatment, the indicators are better than the before treatment, P＆lt;0.05;And Scr, BUN, beta 2-MG, iPTH are superior than conventional treatment after treatment, P＆lt;0.05;Team every other symptoms except mental abnormality rate after treatment were better than the conventional group, P＆lt;0.05;Adverse reaction rates significantly lower than the conventional group, P＆lt;0.05. Conclusion High flux hemodialysis clinical symptoms improved significantly after treatment,and can effectively remove, arge molecular weight of materials, reduce inflammation and so on,better than the low flux hemodialysis, worthy of promotion.
出处
《中国医药指南》
2014年第6期4-6,共3页
Guide of China Medicine
关键词
慢性肾功能衰竭
高通量
血液透析
临床效果
Chronic renal failure
High throughput
Hemodialysis
Clinical effect
