摘要
目的 :观察急性脊髓损伤后脊髓组织和血清中微量元素 (铜锌 )含量的变化 ,研究微量元素与急性脊髓损伤的关系 ,并探讨其可能的发生机理。方法 :用改良 Allen氏脊髓损伤模型 ,选用家兔 3 6只 ,打击能量为 1 2 0 gcf,用原子吸收光谱法测定伤前、伤后 6h,2 4 h,4 8h,72 h和 6d时脊髓组织和血清中的铜锌的含量。结果 :脊髓损伤后血清和脊髓组织中铜含量升高 ,而锌含量则持续性下降。结论 :脊髓损伤后血清和脊髓组织中铜含量升高和锌含量下降在脊髓继发性损伤过程中可能起着重要作用。
Objective:The trace element (TE) level in spinal cord tissue and serum was measured after an acute experimental SCI in order to explain the relation between TE and acute SCI and to explore the possible origination of TE.Methods:The spinal cord Injury model was established by modified Allen's Method.Before SCI and at 6th,24th,48th,72h and 6d after SCI.The TE level in spinal cord and serum was measured by atomic absorption spectroscopy.Results:After SCI,the level of Cu was progressively raised,and the level of Zn was significantly decreased in the spinal cord tissue and serum.Conclusion:Changes of trace element (Cu,Zn)in the spinal cord tissue and serum after SCI might play an important role in SCI.
出处
《中国中医骨伤科杂志》
CAS
2001年第1期14-16,共3页
Chinese Journal of Traditional Medical Traumatology & Orthopedics
基金
研士研究生论文
关键词
脊髓损伤
微量元素
原子吸收光谱法
食量
Spinal cord injury Trace element Atomic absorption spectroscopy
