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同种带瓣大动脉片在肺血少型复杂先天性心脏病手术中的应用 被引量:11

The application of cryopreserved homografts for treatment of complex congenital heart diseases (ten years experience)
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摘要 目的 评价同种带瓣大动脉片在手术矫治肺血少型复杂先天性心脏病 (先心病 )中应用的临床效果。方法  42 0例复杂先心病病人 (儿 )手术中应用了同种带瓣大动脉片 ,其中同种主动脉单瓣补片 2 34例 ,肺动脉单瓣补片 186例。年龄 5个月~ 2 1岁 ,平均 4 6岁。体重 5 5~ 5 2 0kg ,平均 17 5kg。随访 3个月~ 12 3年 ,平均 (2 7 8± 10 3)个月。结果 全组手术死亡率 4 5 % (19 42 0例 ) ;术后机械辅助呼吸 8~ 192h ,平均 (48 6 7± 42 5 0 )h ;术后住院 7~ 46d ,平均 (12± 9)d。无晚期死亡及并发症发生。结论 对于相当一部分肺动脉发育差、以往难以手术根治的病人 (儿 ) ,术中应用同种带瓣大动脉片行右室流出道跨环补片 ,可取得满意手术疗效。 Objective: To evaluate the clinical results of cryopreserved homografts for the treatment of complex congenital heart defects. Methods: In 420 patients with complex congenital heart diseases received surgical correction with right ventricular outflow tract (RVOT) reconstruction was done using cryopreserved homografts. Of the 420 homografts, 234 were aortic homografts and 186 were pulmonary homografts. The mean age of patients was 4.6 years (range, 5 months to 21 years). The mean body weight was 17.5 kg (range, 5.5~52?kg). The mean follow-up time was 27.8 months (range, 3 months to 12.9 years). Results: There were 19 operative deaths with a mortality rate of 4.5%. The postoperative complications occurred in 25 patients and they all recovered uneventfully. The postoperative mechanical ventilation time was 48.7±42.5 hours (range, 8~192 hours). The mean hospital stay was (12.2± 9.0) days (range, 7~46 days). There were no late death and complication. Conclusion: The results of this study suggest that ROVT reconstruction with cryopreserved homografts as transannular patch can be achieved with excellent the clinical outcome.
出处 《中华胸心血管外科杂志》 CSCD 北大核心 2001年第1期9-10,共2页 Chinese Journal of Thoracic and Cardiovascular Surgery
关键词 先天性心脏缺损 人工心脏瓣膜 心脏外科手术 同种带瓣大动脉片 Heart defects, congenital Heart valve prosthesis
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参考文献3

  • 1Ross DN,Somerville J.Correction of pulmonaray atresia with a homograft aortic valve[].The Lancet.1966
  • 2Fontan F,Choussat A,Deville C,et al.Aortic valve homografts in the surgicul trement of complex cardic malformations[].Journal of Thoracic and Cardiovascular Surgery.1984
  • 3Kay PH,Ross DN.Fifteen years experience with the aortic homograft.The conduit of choice for right ventricular outflow tract reconstruction[].The Annals of Thoracic Surgery.1985

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