摘要
目的探讨急性白血病(AL)住院患者医院感染的临床特点,为临床抗生素的使用提供依据。方法对中山大学孙逸仙纪念医院血液内科176例初治AL住院患者完成2次标准化疗方案治疗的临床资料进行回顾性分析,对感染率、感染部位、病原体进行分析。结果例次感染率为47.7%;感染部位:肺部感染例数较多(33.0%);病原菌构成:167例感染中分离出51株病原菌,其中革兰阴性菌27株(52.9%),革兰阳性菌13株(25.5%),真菌11株(21.6%)。结论 AL患者化疗后医院感染率较高,以呼吸道感染居多,革兰阴性菌较多,其次为革兰阳性菌、真菌。
Objective To investigate the clinical characteristics of nosocomial infection of patients with acute leukemia and provide basis for the use of antibiotics in clinic practice. Methods A retrospective analysis of the medical records of 176 pa- tients with acute leukemia after initial treatment was performed, and the infection rate, infection sites, pathogens were analyzed. Results The incidence of nosocomial infection was 47.7% （ 168/352 ） , and respiratory tract was the main infection site. The most common pathogen was gram negative bacilli（27 cases, 52.9% ）, the second was gram positive bacilli（ 13 cases, 25.5% ） , followed by fungi（ 11 cases, 21.6% ）. Conclusion The incidence of nosoeomial infection in patients with acute leukemia after chemotherapy is high and respiratory tract is the main infection site. Gram negative bacilli is the main pathogen, followed by gram positive bacilli and fungi.
出处
《临床医学》
CAS
2014年第2期1-3,共3页
Clinical Medicine
关键词
急性白血病
初治
化疗
医院感染
Acute leukemia
Initial treatment
Chemotherapy
Nosocomial infection
