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急性ST段抬高型心肌梗死患者溶栓成功后肌钙蛋白I水平的变化 被引量：8

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摘要 目的:观察急性ST段抬高型心肌梗死(STEMI)患者尿激酶(UK)溶栓成功后肌钙蛋白I(CTnI)峰值持续时间的变化规律。方法:分析我院收治的应用UK溶栓成功的STEMI患者89例,同时收集病程在12 h内溶栓未成功的STEMI患者98例,非ST段抬高型心肌梗死(NSTEMI)患者88例,监测CTnI及CK-MB峰值及持续时间。结果:溶栓成功STEMI组患者的CK-MB的峰值时间(18.2±3.6)h,CTnI的峰值时间(23.1±9.8)h,分别较NSTEMI患者的CK-MB的峰值时间(28.1±4.2)h及CTnI的峰值时间(31.4±8.9)h明显缩短(P<0.05);溶栓未成功的STEMI患者的CTnI的峰值时间(39.7±8.0)h,其峰值(12.0±9.4)ng/mL较前2组明显升高(P<0.05)。结论:急性心肌梗死后积极的血管再通治疗能显著减少心肌受损;有效血管再通后可能存在再灌注损伤或延迟,导致心肌再次受损。
作者 李斌 王高明 肖闯
机构地区 湖北省松滋市人民医院
出处 《内科急危重症杂志》 2014年第1期44-45,共2页 Journal of Critical Care In Internal Medicine
关键词 急性心肌梗死 溶栓成功 肌钙蛋白I 再灌注损伤
分类号 R542.22 [医药卫生—心血管疾病]
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内科急危重症杂志
2014年 第1期

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