摘要
目的分析130株临床分离的鲍曼不动杆菌(AB)的分布及其耐药性。方法用珠海迪尔公司生产的微生物鉴定和药敏板进行细菌鉴定和药敏试验,收集数据并应用SPSS17.0进行统计分析。结果 2012年在1 391份临床标本中共分离出AB130株,检出率为9.35%。标本主要来源于痰液(89.23%),科室主要分布于重症监护病房(ICU)占46.15%。该菌对头孢哌酮/舒巴坦(舒普深)和多粘菌素B的耐药率最低,分别为6.9%和7.7%,对临床常用的三代头孢的耐药率大于70%,对亚胺培南和美罗培南的耐药率分别为44.6%和58.5%。ICU对13种常见抗菌药物的AB耐药率明显高于非ICU科室(P<0.05)。结论AB对抗菌药物的耐药性日趋严重需引起临床的高度重视,同时还应采取医院感染防控的综合措施以减少耐药菌的传播。
Objective To analyze the distribution and drug resistance of 130 clinical strains of acinetobacter （A ） .baumannii in 2012 .Methods The bacterial identification and the susceptibility test were performed by using the micro-organisms identification and susceptibility plate produced by the Zhuhai Deere Company .The data were collected and statistically analyzed by the SPSS 17 .0 software .Results 130 strains of A .baumannii were isolated from 1 391 clinical samples during 2012 ,the detection rate was 9.35% .Thesamplesweremainlyderivedfromsputum（89.23% ）andthedepartmentwasmainlydistributedinICU（46.15% ）.A. baumannii isolates showed the lowest resistant rates to cefoperazone-sulbactam and polymyxin B ,which were 6 .9% and 7 .7% re-spectively .The drug resistance rate against the third-generation of cephalosporin commonly used in clinic was more than 70% .The resistant rates to imipenem and meropenem were 44 .6% and 58 .5% respectively .The drug resistance rates of A .baumannii isolates to 13 usual antibacterial drugs in ICU were significantly higher than those in non-ICU departments（P＆lt;0 .05） .Conclusion The re-sistance of A .baumannii to antibacterial drugs is gradually serious ,which should be paid high attention to in clinic ,and at the same time the comprehensive measures of prevention and control of hospital infection should be adopted to reduce the spread of drug-re-sistant bacteria .
出处
《国际检验医学杂志》
CAS
2014年第5期576-577,共2页
International Journal of Laboratory Medicine
关键词
鲍氏不动杆菌
抗药性
微生物
微生物敏感性试验
acinetobacter baumannii
drug resistance,microbial
microbial sensitivity tests
