超声引导Cool—tip转换器介导下多针消融离体猪肝的实验研究
摘要
目前,射频消融(RFA)在肝癌的非手术治疗中取得了较好的疗效。Cool—tip射频针由于精准、锐利、操作简单而广泛应用于临床,但其消融范围有限,治疗较大肿瘤时耗时、需要多次进针,且消融过程中产生的气体会影响再次进针,而新开发出的转换器可以同时介导2根或者3根射频针进行消融。本研究旨在通过体外猪肝实验,了解Cool—tip转换器介导下的多针Cool—tip射频针在离体猪肝上所形成的消融范围,为其应用于临床提供依据。
出处
《中华超声影像学杂志》
CSCD
北大核心
2014年第2期165-166,共2页
Chinese Journal of Ultrasonography
参考文献8
-
1Livraghi T,Meloni F,Di Stasi M. Sustained complete response and complications rates after radiofrequency ablation of very early hepatocellular carcinoma in cirrhosis:Is resection still the treatment of choice[J].Hepatology,2008.82-89.
-
2罗葆明,杨海云,文艳玲,智慧,马健鸿,潘景升,王军华.冷循环射频消融治疗肝癌的疗效分析[J].中华超声影像学杂志,2005,14(3):208-211. 被引量:13
-
3Park MJ,Kim YS,Rhim H. A comparison of US-guided percutaneous radiofrequency ablation of medium sized hepatocellular carcinoma with a cluster electrode or a single electrode with a multiple overlapping ablation technique[J].Journal of Vascular and Interventional Radiology,2011.771-779.
-
4Cua IH,Lin CC,Lin CJ. Treatment of hepatocellular carcinoma using internally cooled electrodes.A prospective comparison of modified automated vs.manual pulsed radiofrequency algorithms[J].Oncology,2007,(Suppl 1):76-82.
-
5Laeseke PF,Sampson LA,Haemmerich D. Multiple electrode radiofrequency ablation creates confluent areas of necrosis:in vivo porcine liver results[J].RADIOLOGY,2006.116-124.
-
6Woo S,Lee JM,Yoon JH. Small and medium sized hepatocellular carcinomas:monopolar radiofrequency ablation with a multiple-electrode switching system-mid-term results[J].RADIOLOGY,2013.589-600.
-
7Ji Q,Xu Z,Liu G. Preinjected fluids do not benefit microwave ablation as those in radiofrequency ablation[J].Academic Radiology,2011.1151-1158.
-
8Brace CL,Sampson LA,Hinshaw JL. Radiofrequency ablation:simultaneous application of multiple electrodes via switching creates larger,more confluent ablations than sequential application in a large animal model[J].Journal of Vascular and Interventional Radiology,2009.118-124.
二级参考文献12
-
1Tang ZY. Treatment of hepatocellular carcinoma. Digestion, 1998,59:556-562.
-
2Bruix J. Treatment of hepatocellular carcinoma. Hepatology, 1997,35:259-262.
-
3Bilchik AJ,Rose DM,Allegra DP,et al. Radiofrequency ablation: a minimally invasive technique with multiple applications. Cancer J Sci Am,1999,5:356-361.
-
4Rossi S,Fornari F,Pathies C,et al. Percutaneous ultrasound-guided radio-frequency electrocautery for the treatment of small hepatocellular carcinoma. J Interv Radiol, 1993,8: 97-103.
-
5Livraghi T, Meloni F, Goldberg SN, et al. Hepatocellular carcinoma: radio-frequency ablation of medium and large lesion.Radiology, 2000,214: 761-768.
-
6Solbiati G, Goldberg SN, Ierace T, et al. Hepatic metastases:percutaneous radio-frequency ablation with cooled-tip electrodes.Radiology, 1997,205: 367-373.
-
7Francica G, Marone G. Ultrasound-guided percutaneous treatment of hepatocellular carcinoma by radiofrequency hyperthermia with a "cooled-tip needle": a preliminary clinical experience. Eur J Ultrasound, 1999,9:145-153.
-
8Minami Y,Kono T,Miyazaki T,et al. The IL- 2 receptor compel:its structure, function and target genes. Ann Rev Immunol, 1993,11: 245-268.
-
9Prat F,Centarti M,Sibille A,et al. Extra-corporeal high intensity focused ultrasound for VX2 liver tumors in the rabbit. Hepatology,1995,21:832-836.
-
10王文见.超声治疗肿瘤与免疫[J].国外医学(肿瘤学分册),1998,25(6):347-349. 被引量:42
共引文献12
-
1杨焰,罗葆明,智慧.冷循环射频消融术中二维声像图强回声表现与凝固灶大小的相关性研究[J].中华医学超声杂志(电子版),2007,4(5):311-312.
-
2罗葆明,智慧,文艳玲,段红艳,冯霞,杨海云,谬瑞明.低机械指数谐波超声造影在局灶性肝病治疗适应证选择中的应用[J].中国临床医学影像杂志,2006,17(9):512-514. 被引量:4
-
3王炽秋.超声导引冷循环射频消融肝癌30例临床观察[J].浙江中西医结合杂志,2007,17(9):571-572. 被引量:1
-
4文艳玲,智慧,梁碧玲,冯霞,杨海云,罗葆明.射频消融与不同树突状细胞瘤苗联合治疗实体瘤的实验研究[J].中国超声医学杂志,2007,23(7):490-492.
-
5罗葆明,杨焰,智慧,杨海云,文艳玲.射频消融术中二维声像图强回声区大小与消融范围的相关性研究[J].中华超声影像学杂志,2008,17(2):130-132. 被引量:3
-
6黄国喜,付文生,孔学军,魏国兴.超声造影在经皮微波凝固治疗肝细胞癌前的应用[J].实用医药杂志,2011,28(2):129-130. 被引量:2
-
7潘景升,李高鹏,邓宝雯,马健鸿,王浩虎,罗葆明,陈亚进.术中腹腔镜超声引导射频消融治疗小肝癌的临床探讨[J].上海医学影像,2011,20(2):112-113. 被引量:4
-
8孙崇启,纪海霞,王丽,刘雪皎,王绍凤,王芙霞.超声引导下经皮内冷循环射频消融肝癌的疗效观察[J].中华全科医学,2012,10(9):1402-1403. 被引量:6
-
9黄光亮,谢晓燕,匡铭,徐作峰,刘广健,郑艳玲,吕明德.超声引导下射频消融联合多极无水乙醇注射治疗直径3~7cm肝细胞癌[J].中华超声影像学杂志,2013,22(7):591-594. 被引量:4
-
10周武元,李磊,钟敬涛,崔凯,石学涛.开腹射频消融治疗较大肝肿瘤近期疗效分析[J].中华肝胆外科杂志,2013,19(9):677-680. 被引量:6
-
1崔虎啸,侯森,时永,王芳杰.多针组合射频消融治疗肝脏巨大血管瘤疗效分析[J].中国实用医药,2015,10(25):125-126. 被引量:1
-
2赵宏宇.射频消融技术治疗肝癌的疗效评价[J].现代诊断与治疗,2013,24(1):36-37. 被引量:4
-
3张璐琪,渠效飞,朱晓洁.超声引导射频消融治疗肝脏恶性肿瘤200例肿瘤残留危险因素分析[J].环球中医药,2015,8(S1):33-34.
-
4许若才,李建良,刘寒春,余智渊,孔轶,马国安,李科,欧双艳.射频消融治疗小肝癌的临床研究[J].微创医学,2008,3(1):3-5. 被引量:6
-
5张艳阳,顾仰葵,黄金华,高飞,江雄鹰,张天奇,黄森渺.转换控制器介导的多电极同步消融离体牛肝的影响因素分析[J].中华医学杂志,2015,95(35):2871-2874. 被引量:2
-
6陈宝定,魏金文,薛玉,谢荣,吴新财,邓宏伟,陈德玉.超声引导射频消融治疗小肝癌27例的疗效分析[J].中国医药导报,2012,9(34):62-63. 被引量:7
-
7孙一欣,程文,王秋程,杨洪艳,张丹丹,郭丹阳.超声引导下Cool-tip冷循环射频消融系统治疗大肠癌肝转移的预后因素分析[J].中国超声医学杂志,2013,29(2):130-133. 被引量:8
-
8殷晓煜,谢晓燕,吕明德,陈俊伟,徐辉雄,徐作峰,刘广健,黄蓓.超声引导经皮复合热消融技术治疗中、大肝细胞癌[J].中华外科杂志,2004,42(17):1029-1032. 被引量:21
-
9郭乐杭,徐辉雄,王帅,何勇,刘畅,张一峰,徐军妹,刘琳娜,刘波.超声引导激光消融实验兔肾的有效性评估[J].中华医学超声杂志(电子版),2012,9(11):65-68. 被引量:1
-
10聆风.FDA批准 Cool-tip(TM)系统用于无法手术切除的肝脏肿瘤的治疗[J].中华医学信息导报,2006,21(11):9-9. 被引量:1