摘要
结直肠癌患者容易发生肝转移，手术是目前治疗结直肠癌肝转移的最佳手段。但肝转移的发生时机不同，所采取的手术策略也不同。结直肠癌确诊时发生肝转移的患者，其手术时机一直存在争议；结直肠癌根治术后发生肝转移的患者只要具有手术指征，均应再次实施手术治疗；部分暂不能手术的结直肠癌肝转移患者，多采用化疗、RFA、介入等辅助治疗可使患者重新获得手术机会，但在临床应用中也存在不少困惑。因此，针对不同阶段的结直肠癌肝转移，应采用多学科综合治疗，制订个体化的治疗方案才是改善患者预后的关键。
Colorectal cancer is easily metastasized to the liver. Surgical treatment is the best choice for the treatment of colorectal cancer, while the treatment strategy should be se- lected according to different stages of colorectal liver metastases. Liver metastases occurred at the definite diagnosis of colorectal cancer or within 6 months after radical resection of colorectal cancer are synchronous liver metastases, the timing of synchro- nous liver metastases resection is still under controversy. Liver metastases occurred at 6 months after radical resection are meta- chronous liver metastases, and for patients with metachronous liver metastases, reoperation should be applied if the indications are clear. Chemotherapy, radiofrequency ablation and interven- tional therapy provide chances of reoperation for patients who originally cannot received surgical treatment, while confusion exists in their clinical application. Therefore, multi-disciplinary treatment based on individualized condition evaluation is the key point in improving the prognosis of patients with colorectal liver metastases in different stages.
出处
《中华消化外科杂志》
CAS
CSCD
北大核心
2014年第3期165-167,共3页
Chinese Journal of Digestive Surgery
基金
国家自然科学基金（30972894、81272688）
关键词
结直肠肿瘤
肝转移
外科手术
Colorectal neoplasms
Liver metasta-ses
Surgical procedures, operative
