摘要
目的探讨饮用高砷水对机体尿素氮水平的影响。方法以2个地区(高砷区和对照区)的常住成年居民为调查对象,采集晨尿及空腹静脉血,同时采集受访者家中饮用水水样。用原子吸收法测水总砷,用苦味酸比色法检测尿肌酐,采用酶偶联速率法测尿素氮。结果饮水型砷中毒病区居民血清尿素氮平均水平(5.08 mmol/L)高于非高砷区居民(3.60 mmol/L),二者差异显著(P=0.0239);饮水型砷中毒病区居民饮用水总砷浓度与血清尿素氮水平呈正相关关系(r=0.293,P=0.023)。结论饮用高砷水对居民肾脏存在潜在危害。
Objective To evaluate the influence of high arsenic drinking water on the concentration of urea nitrogen. Method We chose permanent residents from area of drinking-water type endemic arsenism and control area as the investigation objects; we collected fasting venous blood,morning urine and drinking water sample of the investigation objects. Total arsenic concentration was tested by atomic absorption method; the concentration of urine creatinine examined by the picric acid colorimetry method,the method of enzyme coupling ratio was used to examine the concentration of urea nitrogen. Results The average concentration（ 5. 08 mmol / L） of serum urea nitrogen of the objects living in the area of drinking-water type endemic arsenism is higher than the concentration（ 3. 60 mmol / L） of the objects living in the control area,the difference was statistically significant（ P = 0. 0239）; there is a positive correlation between the arsenic concentration in drinking water and the levels of serum urea nitrogen concentration of the objects living in the area of drinking-water type endemic arsenism（ r = 0. 293,P = 0. 023）. Conclusion Drinking water with high arsenic may be a potential risk for kidney.
出处
《中国地方病防治》
CAS
2014年第1期35-36,共2页
Chinese Journal of Control of Endemic Diseases
关键词
尿砷
血清尿素氮
尿肌酐
Urinary arsenic
Serum urea nitrogen
Urine creatinine
