摘要
目的观察红花黄色素(SY)治疗脑外伤后脑心综合征的临床疗效。方法将52例脑心综合征患者随机分为治疗组和对照组,每组各26例。两组均给予常规治疗(降颅压、控制血压、营养神经、止血、抗感染、护胃及对症支持治疗),治疗第3 d时,对照组继续给予常规治疗;而治疗组在常规治疗的基础上,静脉滴注红花黄色素。两组均治疗10 d。观察两组治疗前后的临床症状、心电图和生化指标(肌钙蛋白I(TnI)、心肌酶谱的改善情况。结果治疗组治愈率为61.5%,总有效率为96.2%;对照组治愈率为30.8%,总有效率为69.2%,两组间比较有统计学差异(P<0.05)。治疗组TnI和CK-MB下降较对照组更明显(P<0.01)。结论红花黄色素治疗脑外伤后脑心综合征有较好的临床疗效,且安全性高。
Objective To observe the clinical curative effects of safflower yellow （SY） on cerebro-cardiac syndrome after craniocerebral trauma. Methods Fifty two patients with cerebro-cardiac syndrome were randomly divided into treatment and control groups with 26 cases in each group. Both groups were treated by routine therapy including decreasing the intracranial pressure, controlling blood pressure, nerve nutrition, hemostasis, anti-infection, stomach protection, and symptomatic supportive treatment. On the third day of the treatment, the control group continuously received the conventional treatment, while based on the conventional therapy, the treatment group received the intravenous drip with SY. Both groups received the treatment for 10 d. Observation was made in the clinical symptoms, the electrocardiogram, the improvement of biochemical indicators （TnI and CK-MB） before and after the treatment in both groups. Results In the treatment group, the cure rate was 61.5%, and the total effective rate was 96.2%. In the control group, the cure rate was 30.8%, and the total effective rate was 69.2%. There were significant differences between the two groups （P 〈 0.05）. The decrease of TnI and CK-.VIB in the treatment group was more significant than that in the control group （P 〈 0.01 ）. Conclusion SY has good therapeutic effect on cerebro-cardiac syndrome after craniocerebral trauma and also high safety.
出处
《西南国防医药》
CAS
2014年第3期268-270,共3页
Medical Journal of National Defending Forces in Southwest China
关键词
红花黄色素
磷酸肌酸
脑心综合征
肌钙蛋白I
疗效
safflower yellow
phosphocreatine
cerebro-eardiae syndrome
troponin I
curative effect
