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神经节苷脂治疗血管性痴呆的临床研究 被引量:4

Clinical study on the Efficacy of Ganglioside in the Treatment of Vascular Dementia
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摘要 目的探讨神经节苷脂治疗血管性痴呆的临床效果。方法将64例血管性痴呆患者随机分为治疗组与对照组,各为32例,两组患者均予常规治疗,治疗组患者在此基础上同时采用神经节苷脂静滴治疗,对照组患者采用胞二磷胆碱治疗,观察两组患者简易精神状态量表(MMSE)和日常生活能力量表(ADL)评分。结果治疗组患者MMSE和ADL评分明显优于对照组,差异有统计学意义(P<0.05)。结论神经节苷脂治疗血管性痴呆效果显著,能够改善患者认知力及日常生活能力,且安全性好。 Objective To explore the clinical effect of Ganglioside on vascular dementia. Methods 64 patients with vascular de- mentia were randomly divided into treatment group and control group with 32 cases in each. On the basis of conventional treat- ment, the treatment group was given intravenous drip of Ganglioside for treatment, while the control group was given Citicoline for treatment. The two groups were observed, and evaluated by Minimum Mental State Examination(MMSE) and Activity of Daily Liv- ing Scale(ADL). Results The scores of MMSE and ADL of the treatment group were significantly higher than those of the control group, the difference was statistically significant(P〈0.05). Conclusion Ganglioside has significant effect on vascular dementia, which can improve the cognitive ability and activity of daily living of the patients with good security.
出处 《中外医疗》 2014年第4期9-9,18,共2页 China & Foreign Medical Treatment
关键词 神经节苷脂 血管性痴呆 MMSE ADL Ganglioside Vascular Dementia MMSE ADL
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