摘要
控制性超排卵过程中,不同患者对外源性促性腺激素的反应性存在个体差异。常用预测指标包括年龄、卵泡刺激素(FSH)、窦卵泡数(AFC)和卵巢体积、抗苗勒管激素(AMH)、基础抑制素B(bINHB)、基础雌二醇(bE2)、克罗米芬兴奋试验、联合预测等,其中AMH和AFC最为可靠。卵巢反应性的预测可为用药方案、剂量选择提供有力依据,是制定个体化治疗的关键。
During controlled ovarian hyperstimulation(COS),there are individual differences of the responses to exogenous gonadotropin among patients. Common predictors include ages, follicle stimulating hormone(FSH), antral follicle count (AFC) and ovarian volume, antimtillerian hormone (AMH), basal inhibin B, basal Estradiol(hE2 ), clomiphere citrate challenge test, etc. Among them, AMH and AFC are the most reliable ones. The prediction of ovarian response can provide powerful evidence to COS protocol and dose selection, which is important for the individual treatment.
出处
《生殖医学杂志》
CAS
2014年第2期155-159,共5页
Journal of Reproductive Medicine
关键词
卵巢反应
抗苗勒管激素
抑制素B
卵泡刺激素
窦卵泡计数
Ovarian response
Antimiillerian hormone
Inhibin B
Follicle stimulating hormone
Antralfollicle count