摘要
目的 :观察兔角膜上皮广泛丧失对角膜形态的影响。方法 :用大耳白兔 2 0只 ,随机分为两组 ,左眼为实验眼 ,右眼作对照眼。将一组兔左眼角膜中央 8mm上皮刮除 ,另一组兔左眼角膜上皮广泛刮除 ,仅保留角膜缘部0 .2 mm上皮。术后每日观察角膜上皮愈合情况 ,4周后测量角膜厚度、前房深度、角膜中央曲率。结果 :广泛刮除角膜上皮眼上皮愈合时间明显延长 ,角膜厚度明显变薄 ,前房深度明显变深 ,角膜中央曲率明显变大。结论 :兔角膜上皮广泛丧失可使角膜变薄 。
Objective: Our purpose was to observe the effect of epithelial scrape injury on corneal morphology. Methods: Twenty 4 week old white rabbits were used. We scraped the corneal epithelia of the left eye of each rabbit (0.2 mm near the limbus of corneal were left in 10 eyes, in the remaining rabbits within 8 mm in the center). The right eyes were control group. We observed the healing of corneal protrusion with slit lamp microscope, examined the corneal form with corneal topography, and measured the depth of anterior chamber and the corneal thickness with A ultrasound. Results: The extensive epithelial scrape significantly increased the healing time. The corneal protrusion of experimental group and the depth of anterior chamber increased. The corneal thickness became thinner. Conclusion: The extensive epithelial injury can make cornea thinner, which results in the changes of corneal protrusion.
出处
《中国医科大学学报》
CAS
CSCD
北大核心
2001年第1期20-21,共2页
Journal of China Medical University
