摘要
目的:探讨冠脉造影患者血小板活化因子(platelet-activating factor,PAF)水平与冠状动脉病变支数的相关性。方法:将128例可疑冠心病患者按冠脉造影结果分为:健康对照组(21例)、冠心病组(107例)。冠心病组记录冠脉病变支数。用酶联免疫法(ELASA)测量血浆PAF浓度,分析其与冠状动脉病变支数的相关性。结果:PAF浓度与冠状动脉病变支数呈正相关,差异有统计学意义(P<0.05)。结论:PAF浓度水平有望作为冠心病病情监测的指标。
Objective: To investigate the correlation between platelet-activating factor(PAF) and the number of stenosed coronary vessels in patients with coronary angiography ( CAG). Methods : 128 cases with suspected CHD were divided into groups according to coronary angiography, including 21 normal cases, 107 patients with CHD, whose number of stenosed coronary vessels was recorded. The PAF concentrations were detected by ELISA, and the relationship between PAF concentrations and the number of stenosed coronary vessels was analyzed. Results: There were positive correlations between the PAF levels and the number of stenosed coronary vessels, the differences were statistically significant (P 〈 0. 05 ). Conclusion : PAF concentrations are related with the degree of coronary artery stenosis and may serve as an available index for the severity of CHD.
出处
《河南医学研究》
CAS
2014年第1期19-21,共3页
Henan Medical Research
关键词
冠心病
冠状动脉狭窄
血小板活化因子
冠脉造影
coronary disease
coronary stenosis
platelet-activating factor
coronary angiography