期刊文献+

胃肠间质瘤的临床诊断与外科治疗分析 被引量:2

Analysis of Clinical Diagnosis and Surgical Treatment of Gastrointestinal Stromal Tumor
暂未订购
导出
摘要 目的探讨胃肠间质瘤(GIST)的诊断和治疗。方法回顾性分析2004年8月至2013年9月收治的经手术治疗的24例GIST病人的临床资料。结果 24例病人均行手术,术后病理确诊为GIST。其中胃18例,小肠6例。24例完整手术切除。所有病例均随访,4例于术后1-3年发现肿瘤复发伴肝脏、腹腔转移,无法手术死亡。结论 GIST起病隐匿,早期确诊相对困难,首选治疗方法是根治性切除,术后辅助应用甲磺酸伊马替尼可减少复发和改善预后。 Objective To explore the method for diagnosis and treatment of gastrointestinal stromal tumor (GIST). Mothods The clinical data of 24 cases of GIST treated by surgical operation in this hospital from August 2004 to September 2013 were retrospectively analyzed. Results These 24 patients had been operated and GIST had been proved by pathological examination. In this series of patients, the tumor had been found in stomach (n=18) , small intestine (n=6) . GIST in 24 cases had completely been resected .All of the case were followed up.In 4 cases of 1-3 years of tumor recurrence was found with the liver, peritoneal metastasis, no operation death. Conclusion GIST insidious onset, early diagnosis is difficult.The first choice for treatment of GIST is curative resection, and adjuvant therapy with imatinib mesylate can reduce the recurrence of tumor, thus it may improve the prognosis and raise the survival rate of patients.
出处 《罕少疾病杂志》 2014年第1期9-12,共4页 Journal of Rare and Uncommon Diseases
关键词 胃肠间质瘤 临床诊断 外科手术 甲磺酸伊马替尼 Gastrointestinal stromal tumors, Clinical diagnosis, Surgical operation, Imatinib mesylate
  • 相关文献

参考文献14

二级参考文献137

共引文献83

同被引文献33

  • 1佟铸,刘彤,张宝良,王鹏志.原发性小肠淋巴瘤30例诊治分析[J].天津医科大学学报,2006,12(1):41-43. 被引量:13
  • 2Duffaud F, Blay J Y. Gastrointestinal stromal tumors: bi- ology and treatment [ J ]. Oncology, 2003,65 ( 3 ) : 187- 197.
  • 3Yokoi K, Yamashita K, Tanaka N, et al. Gastrointestinal stromal tumor of the stomach diagnosed preoperatively [J]. J Nippon Med Sch, 2001,68(5) :435-441.
  • 4Casali P G, Blay J Y. Gastrointestinal stromal tumours: ESMO Clinical Practice Guidelines for diagnosis, treat- ment and follow-up [ J ]. Ann Oncol, 2010,21 ( Suppl 5iN) :98-102.
  • 5Fletcher C D, Berman J J, Corless C, et al. Diagnosis of gastrointestinal stromal tumors: A consensus approach [ J ]. Hum Pathol, 2002,33 ( 5 ) :459-465.
  • 6Koehhar R, Manoharan P, Leahy M, et al. Imaging in gastrointestinal stromal tumours: current status and future directions [ J ]. Clin Radiol, 2010,65 ( 8 ) :584-592.
  • 7Hornick L J, Fletcher C D. The role of KIT in the man- agement of patients with gastrointestinal stromal tumors [J]. HumPathol, 2007,38(5):679-687.
  • 8史伟,王强,李州利,石炳毅,蔡明.直肠部位胃肠间质瘤1例报告并文献复习[J].中国误诊学杂志,2008,8(3):735-736. 被引量:2
  • 9唐永华,陈克敏,钟捷,吴志远,朱晖,缪飞.原发性小肠淋巴瘤的多层螺旋CT诊断[J].诊断学理论与实践,2008,7(1):42-46. 被引量:21
  • 10刘骞.直肠间质瘤的外科治疗[J].实用肿瘤杂志,2009,24(2):102-103. 被引量:10

引证文献2

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部