摘要
目的探讨胸腔积液中腺苷脱氨酶(ADA)测定值对结核性胸膜炎的诊断意义和应用价值。方法 366例住院的胸腔积液患者,分别行结核菌素纯蛋白衍生物(PPD)试验,同时应用酶速率法检测胸腔积液中ADA值及其与血清中ADA比值,比较其特异性及灵敏度。结果 ADA>45 U/L对诊断结核性胸膜炎的敏感度(94.04%)、特异度(88.8%)均较高,高于PPD敏感度(90.18%)、特异度(82.1%),二者差异有显著性(P<0.05)。结论胸腔积液中ADA含量的检测对于早期诊断及治疗结核性胸膜炎具有积极意义。
Objective To study the relationship between theADA rising in pleural effusion and tuberculous pleuritis, so as to prefer early chemotherapy. Methods 336 cases with pleural effusion were tested with PPD and ADA activity was determined by enzyme kinetic analytical method respectively at the same time. Hydrothorax ADA for diagnosis in patients with tubeiculous pleurisy. Results Statistical analysis suggest significant differences of sensitivity and specificity between ADA and PPD （P＆lt;0.05）. the former sensitivity was higher （94.04%） and specificity （88.8%） than that of the later （90.18%）, （82.1%）. Conclusion ADA test has active value in early for tuberculous pleural effusion and its chemotherapy.
出处
《中国医药指南》
2014年第4期37-37,39,共2页
Guide of China Medicine
