摘要
直立性高血压（OHT）是指从卧位变为直立位后血压升高，其发生机制涉及下肢静脉池扩大、交感神经激活、神经体液因子改变及压力反射敏感性增高。OHT的诊断主要依靠直立倾斜试验。OHT与高血压、冠状动脉疾病及无症状脑梗死密切相关，可能是心脑血管疾病新的预测因子和高血压靶器官损伤的长期评估指标。目前对儿童OHT研究较少，由于血压存在一定程度的轨迹现象，对儿童OHT的深入研究能更好地预测成年期心脑血管疾病风险和评估靶器官损害。
Orthostatic hypertension （OHT） is defined as an increase in blood pressure from supine to orthostatic position. Its mechanism involves a greater venous pooling in the lower extremities, sympathetic activation, change of neurohumoral factors and hypersensitivity of baroreflex. The diagnosis of OHT mainly depends on head-up tilt test. OHT is closely related to hypertension, coronary artery diseases and asymptomatic cerebral infarction. It might be a new predictor of cardiovascular and cerebrovascular diseases and a long-term marker for evaluating target organs damage in hypertension. Studies about OHT in children are rare. To some extent, blood pressure exists tracking phenomenon, further study of OHT in children is beneficial to predict the risk of cardiovascular and cerebrovascular disease and evaluate the target organ damage in adulthood.
出处
《中华实用儿科临床杂志》
CAS
CSCD
北大核心
2014年第1期2-5,共4页
Chinese Journal of Applied Clinical Pediatrics
基金
基金项目：“十二五”国家科技支撑计划（2012BA103803）
湖南省自然科学基金（13JJ5014）
湖南省卫生厅资助项目（B2013-013）
