摘要
目的 探讨电针对恢复期局灶性脑缺血大鼠的治疗作用。方法 通过结扎大鼠一侧大脑中动脉 (middle cerebral artery occlusion,MCAO)造成局灶性脑缺血，研究电针对恢复期模型大鼠神经病学、被动性条件反射、血液流变性、脑梗死面积及脑组织病理学指标的影响。结果 电针能改善模型大鼠恢复期神经病学症状，提高记忆能力，显著缩小脑梗死面积，促进坏死灶内新生毛细血管和胶质细胞增生修复，对血液粘度无明显影响的。结论 电针对大鼠局灶性脑缺血具有明显的治疗作用。
Objective To observe the effects of EA on recovery of focal cerebral ischemia in rats.Method Focal cerebral ischemia was pruduced in rats by the right middle cerebral artery occlusion(MCAO).The therapeutic action of EA on focal cerebral ischemia was studied by investigating the change of weight,nervous symptoms,passive conditional reflex,rheology,infarct size of brain and pathology of brain tissue.Result EA could not onlyoimprove obviously nervous symptoms,prolong memory and lessen infarct size,but also promote proliferation and reqair of gliocyte and neogenetic capillary in the malactic and necrotic regions and reduce the edema and inflammatoey reaction around necrotic region,but not effect the blood viscosity in recovery MCAO rats.Conclusion EA hastherapeutic action on recovery of focal cerebral ischemia in rats.
出处
《现代康复》
CSCD
2001年第2期62-63,共2页
Modern Rehabilitation
基金
国家自然科学基金资助项目! (39270837)
