摘要
目的研究罗哌卡因、左旋布比卡因在硬膜外分娩镇痛中的应用效果。方法回顾性分析2011年4月—2013年2月入住我院产科分娩的54例初产妇的临床资料,按照产妇分娩期间采用的不同镇痛药物,将54例产妇分为两组,每组27例。两组产妇均采用硬膜外麻醉方式处理和芬太尼镇痛,对照组产妇分娩期间采用加用浓度为0.1%的左旋布比卡因,观察组产妇加用浓度为0.1%的罗哌卡因。比较两组产妇分娩期间的麻醉起效时间、下肢运动能力、产程时间等。结果两组产妇各麻醉效果分级间比较,差异无统计学意义(P>0.05)。两组产妇VAS评分及镇痛起效时间比较,差异无统计学意义(P>0.05),观察组Bromage评分低于对照组,差异有统计学意义(P<0.05)。两组产妇的不同产程时间比较,差异无统计学意义(P>0.05)。结论产妇分娩期间采用罗哌卡因、左旋布比卡因行硬膜外麻醉分娩镇痛均可达到麻醉镇痛的目的,二者效果接近,但是罗哌卡因的运动阻滞时间较短,更适用于临床分娩镇痛。
Objective To discuss the effect of ropivacaine and levobupivacaine in the treatment of epidural labor anal- gesia. Methods 54 pregnanr women from Apr. 2011 to Feb. 2013 were divide into study group and controlled group by differ- ent analgesics. All these two groups were treated with epidural anesthesia, the controlled group were treated with levobupiva- caine, the study group were treated with ropivacaine. The analgesic effect of time, labor, VAS pain score of these two groups were compared. Results The two groups were compared between theanesthesia effects of grading, the difference was no signifi- cant difference （P 〉 0. 05）. Two groups were compared withVAS score and the onset time of analgesia, the difference was no significant difference （P 〉0. 05）, the observation groupBromage were lower than those of the control group, the difference was statistically significant （P 〈 0. 05）. The two groups were compared in different stage of labortime, the difference was no signifi- cant difference （P 〉 0. 05）. Conclusion Using ropivacaine to epidural labor analgesia can short motor blockade to extend in clinic.
出处
《临床合理用药杂志》
2014年第6期42-44,共3页
Chinese Journal of Clinical Rational Drug Use
关键词
罗哌卡因
左旋布比卡因
麻醉
硬膜外
镇痛
产科
神经肌肉阻滞
Ropivacaine
Levobupivacaine
Anesthesia, epidural
Analgesia, obstetrical
Neuromuscular blockade
