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血清胆碱酯酶与脑梗死的相关性研究 被引量:4

Correlation study of serum cholinesterase with cerebral infarction
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摘要 目的探讨急性脑梗死患者血清胆碱酯酶(CHE)水平与脑梗死的关系。方法将急性脑梗死患者分为非大面积脑梗死组和大面积脑梗死组,对脑梗死患者与正常对照组进行血脂、血糖、血清胆碱酯酶活性的测定。结果非大面积脑梗死组血清胆碱酯酶活性较对照组升高,大面积脑梗死组血清胆碱酯酶活性较对照组降低(P〈0.01),多元线性回归分析提示血糖、三酰甘油、总胆固醇与血清CHE水平呈正相关(P〈0.05)。Logistic回归分析显示,血清CHE水平与脑梗死发生密切相关(P〈0.01)。结论血清胆碱酯酶水平与脑梗死发生及病情严重程度密切相关。 Objective To investigate the relationship between serum cholinesterase levels and cerebral infarction in patients with acute cerebral infarction. Methods Patients with acute cerebral infarction were divided into non-large size cerebral infarction group and large size cerebral infarction group. The levels of blood lipid, blood glucose, serum cholinesterase activity were detected in cerebral infarction group and control group. Results The serum cholinesterase activity was higher in non-large area cerebral infarction group than that in control group, the serum cholinesterase activity was lower in large area infarction group than that in control group ( P 〈 0. 01 ), multiple linear regression analysis showed that blood glucose, triglyceride, total cholesterol were positively correlated with the level of serum CHE(P 〈 0. 05 ). Logistic regression analysis showed that, the serum level of CHE was closely correlated with cerebral infarction(P 〈 0. 01 ). Conclusions Serum cholinesterase level is closely related to the occurrence of cerebral infarction and the severity of the disease.
作者 刘馨 潘旭东
出处 《中国实用医刊》 2014年第6期7-9,共3页 Chinese Journal of Practical Medicine
关键词 胆碱酯酶 脑梗死 血脂 血糖 Cholinesterase Cerebral infarction Blood lipid Blood glucose
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