摘要
目的 探讨胱抑素C（CysC）对临床常见心血管疾病-冠心病的临床预测价值.方法取152例经冠状动脉造影确诊患者的肘静脉血3-4 mL,分离血清,于全自动生化分析仪测定CysC的浓度,分别与非冠心病对照组比较.结果四个组在性别、年龄、血脂、血糖方面的比较均无统计学意义（P〉0.05）,具有可比性;AMI组的UA测定明显高于对照组,差异有显著性（P ＜0.05）;UAP组和AMI组血清hs-CRP水平明显高于SAP组和对照组（P ＜0.05）,且AMI组的hs-CRP水平显著高于UAP组（P ＜0.05 ）;UAP组和AMI组的CysC水平明显高于SAP组和对照组（P ＜0.05）,AMI组CysC水平明显高于UAP组（P ＜0.05）.结论 CysC参与了冠心病的发生和发展,是冠心病预后不良的一个重要预测因子.
Objective To explore the clinical predictive value of CysC on coronary heart disease-a clinical common cardiovascular disease. Methods One hundred and fifty-two coronary heart disease patients diagnosed by coronary angiography were chosen to take 3-4 mL blood of each patient from their cubital veins. The serum was isolated to test the concentration of CysC by automatic biochemical analyzer. The results were compared with those of the non-coronary disease group （the control group）. Results The comparisons between each two groups of the four groups in gender, age, blood lipid and blood glucose were not statistically significant （P〉0.05）. The UA value of AMI group was much higher than that of the control group and the difference was significant （P 〈0.05）. The serum hs-CRP levels of UAP group and AMI group were much higher than those of SAP group and control group （P 〈0.01）, and the serum hs-CRP level of AMI group was significantly higher than that of UAP group（P 〈0.01）. The CysC levels of UAP group and AMI group were significantly higher than those of SAP group and control group（P 〈0.05）, and the CysC level of AMI group was significantly higher than that of UAP group （P 〈0.05）. Conclusion CysC is involved in the occurrence and development of coronary heart disease, therefore is an important predictor for unfavorable prognosis of coronary heart disease.
出处
《中国现代医生》
2014年第7期90-92,共3页
China Modern Doctor
关键词
稳定型心绞痛
急性心肌梗死
心血管不良事件
超敏C反应蛋白
胱抑素C
Stable angina pectoris
Acute myocardium infarction
Major adverse cardiovascular events
High-sensitive c-reactive protein
CysC
