摘要
目的 总结膀胱引流术式胰、肾联合移植经验和教训。方法 对 2例胰岛素依赖型糖尿病并发尿毒症患者施行膀胱引流式胰、肾联合移植 ,术后早期采用皮质激素、霉酚酸酯 (MMF)、环孢素A(CsA) /他克莫司 (FK5 0 6 )和抗淋巴细胞球蛋白 (ALG)进行免疫抑制治疗 ,8～ 10d后改为FK5 0 6、MMF和泼尼松维持。结果 移植后 ,2例均立即停用胰岛素 ,肾功能逐渐恢复正常 ,仅例 2术后并发轻微切口感染 ,经引流、局部处理后愈合 ,无其它外科并发症 ,未发生排斥反应 ,患者目前已分别存活 6个月和 2个月 ,移植胰和移植肾功能均正常 ,一般情况良好。结论 膀胱引流式胰。
Objectives To summarize the clinical technique and experience of simultaneous kidney pancreatic transplantation (SKPT) with bladder drainage.Methods From Jan. to May, 2000,2 patients with insulin dependent diabetes mellitus/end stage renal disease underwent SKPT with bladder drainage of exocrine secretions. The patients were treated with quadruple therapy including antilymphocyte globulin (ALG) induction therapy, prednisone, cyclosporine A/tacrolimus, and mycophenolat mofetil (MMF), as maintenance immunosuppression. Results Both patients became insulin independent postoperatively. Until now all the grafts from two patients were functioning well (6 and 2 months respectively). Except for slight wound infection occurred in case 2, no other complications occurred. Conclusion SKPT with bladder drainage is a simple, safe and effective therapy for type I diabetes mellitus with uremia.
出处
《中华器官移植杂志》
CAS
CSCD
北大核心
2001年第1期27-29,共3页
Chinese Journal of Organ Transplantation
