摘要
目的观察脑梗死患者发病前血浆D-二聚体(D-Dimer)、同型半胱氨酸(Hcy)及血黏度的变化,探讨其与脑梗死发生的关系。方法采用回顾性统计调查94例脑梗死患者的检测数据,同时选取本院健康体检者102例作为对照组。免疫比浊法测定血浆D-二聚体和纤维蛋白原(FIB),酶法测定Hcy,放射免疫法测定叶酸(FA)及维生素B12(VitB12)含量。结果脑梗死患者发病前72h内血浆D-二聚体、FIB及Hcy水平显著高于对照组(P<0.05),FA、VitB12水平明显低于对照组(P<0.05),患者全血及血浆黏度均高于对照组(P<0.05)。结论血黏度增加伴有高D-二聚体和Hcy血症可能是脑梗死的促发因素之一。
Objective To investigate the relationship between plasma D-D dimer, homocysteine（ Hcy）, blood vis- cosity levels and cerebral infarction. Methods Ninety-four patients with cerebral infarction and 102 healthy persons （control group） were enrolled and observed.The levels of D-D dimer, fibrinogen（ FIB）, Hcy, folic acid（ FA）, VitB12 were detected by immune turbidimetry, enzyme and RIA respectively （0-72 h before the stroke）. Results The levels of D-di- mer, FIB, Hcy and blood viscosity were significantly higher and the plasma levels of FA and VitB12 were lower in the pa- tients with cerebral infarction than those in control group（P〈0.05）. Conclusions High levels of plasma D-dimer, ho- mocysteine and blood viscosity may be the risk factors for stroke.
出处
《实用老年医学》
CAS
2014年第2期141-143,共3页
Practical Geriatrics
