摘要
目的了解中青年人群发生缺血性脑梗死的临床特征和预后情况,为预防中青年脑梗死的发生提供参考依据。方法以2008年1月-2013年6月住院治疗的缺血性脑梗死患者为研究对象,回顾性分析中青年脑梗死患者与老年脑梗死患者在临床特征或预后等方面存在的不同。结果共纳入547例缺血性脑梗死患者,其中中青年患者233例,老年患者314例;中青年组中男性患者的比例显著高于老年组。相对于老年组患者,中青年组患者合并高血压的比例相对较低(51.9%,64.3%;P=0.004),但吸烟(51.9%,36.3%;P=0.000)和长期饮酒(53.2%,28.3%;P=0.000)等不良生活习惯率显著增高。此外,中青年组患者合并血管畸形的比例显著高于老年组患者(7.3%,3.2%;P=0.028)。在治疗方面,中青年组患者接受溶栓治疗和抗血小板治疗的比例显著高于老年患者(98.3%,86.9%;P=0.000),且中青年组患者预后显著好于老年组患者。结论中青年缺血性脑梗死患者预后相对较好,改善不良生活习惯可能是减少中青年缺血性脑梗死发生的有效措施。
Objective To explore the clinical features and prognosis of ischemic cerebral infarction in young population, and to provide a reference for clinical prevention of cerebral infarction in young population. Methods A total of 547 patients with ischemic cerebral infarction diagnosed between January 2008 and June 2013 were included, and the difference in clinical data and outcomes between young and old patients were retrospectively compared. Results The 547 patients included 233 young and 314 old patients, and there were more male patients in young group. As compared to the old group, the proportion of hypertension was significantly lower in young group （51.9%, 64.3%; P=0.004）; while smoking （51.9%, 5.7%; P=0.000） and alcoholism （53.2%, 28.3%; P=0.000） were significantly higher in young group. Moreover, there were more patients with vascular malformations in young group than that in old group （7.3%, 3.2%; P=0.028）. And there were also more patients in young group received thrombolytic therapy and antiplatelet therapy （98.3%, 86.9; P=0.000）, and the prognosis of young patients was significantly better than that of old patients. Conclusion The prognosis of young patients with ischemic stroke prognosis is relatively good, and changing bad habits would be an effective measure to prevent and reduce the occurrence of ischemic cerebral infarction in young population.
出处
《华西医学》
CAS
2014年第2期214-216,共3页
West China Medical Journal
关键词
中青年
老年
缺血性脑梗死
临床特征
预后
Young
Elderly
Ischemic cerebral infarction
Clinical feature
Prognosis
