摘要
本文报道了69例矽肺病人和31例年龄配对的健康男性的血清-微球蛋白(-m)的放射免疫测定。结果表明,Ⅰ期矽肺病人血清β_2-m的X±S为2.13±0.70;Ⅱ期为4.52±2.08;Ⅲ期为4.74±1.80μg/ml,均显著高于对照组,且随矽肺病人病情进展而增高。Ⅰ期矽肺病人血清β_2-m含量,有症状组高于无症状组。本文对血清β_2-m在各期矽肺病人体内检出的特异性、假阳性、假阴性率敏感性,以及对矽肺免疫的意义作了扼要讨论。
A radioimmunoassay of serum β2-microglobulin (sβ2-m) in 69 cases of lilicosis diagnosed by chest x-ray and 31 age-matched healthy male adults as controls was reported.The mean values of sβ2-m in cases of silicosis at stage Ⅰ,Ⅱ and Ⅲ were 2.13±0.70,4.52±2.08 and 4.74±1.80μg/ml respectively which werefound higher than that of age-matched controls at a significance level of 0.001. It was also demonstrated that the sβ2-m levels increased with the severity of silicosis,and in cases with complications. The specificity, false positive, false negative sensitivity of the method and its immunological as well as diagnostic significance in relation to silicosis was briefly discussed.
出处
《工业卫生与职业病》
CAS
CSCD
1991年第3期136-139,共4页
Industrial Health and Occupational Diseases
关键词
矽肺
Β2-微球蛋白
测定
silicosis
β2-microglobulin
radioimmunoassay
