摘要
子痫前期(preeclampsia,PE)是一种妊娠期危及母儿安全的严重并发症,也是妊娠期母儿发病和死亡的重要原因,常累及心、脑、肝、肾和胎盘等重要器官,发生多器官功能障碍,表现为高血压、水肿、蛋白尿、凝血机制障碍、头痛、胎儿生长受限等。近年来,人们对PE的发病机制进行了大量的研究,但其具体病因仍不十分明确。及时准确的诊断和治疗,适时终止妊娠,积极器官支持,有效的改善母儿预后显得尤为重要。
Preeclampsia is a serious pregnancy complication endangering mother and fetus. It is also considered as the leading cause of fetomaternal morbidity and mortality, and often affects the major maternal organs as heart, brain, liver, kidney and placenta. It can lead to multiple organ dysfunction syndromes (MODS), manifested as hypertension, edema, proteinuria, coagulation disorders, headaches, fetal growth restriction( FGR)et al. Currently, a lot of reseaehes have been done to explore the pathogenesis of preeclampsia, however, it's remain unclear. So it is important to make timely and accurate diagnosis and treatment, active organ support, timely termination of pregnancy to improve maternal and neonatal outcomes.
出处
《中国计划生育和妇产科》
2014年第1期13-17,45,共6页
Chinese Journal of Family Planning & Gynecotokology
关键词
子痫前期
并发症
多器官功能障碍
preeclampsia
complication
multiple organ dysfunction syndromes