摘要
microRNAs(miRNAs)是一类19-25tit的小分子非编码RNA,通过与靶基因3′-UTR互补配对介导靶基因转录后调控,在生物的生命过程中扮演着十分重要的角色。miRNA作为机体重要的调控子,参与动物生长、发育、疾病等过程。目前,对miRNA的研究已经成为生命科学领域中的热点。作者综述了miRNA对肌肉的发育调控及动物发育miRNA鉴定的最新研究进展。
mieroRNAs (miRNAs) are a class of short (19 to 25 nt) non-coding RNAs that negatively regulate gene expres- sion at the post-transcriptional level by binding with 3′-UTR of the target gene. microRNAs play the important roles in the fundamental biological processes, microRNAs involved in the regulation of growth, development and diseases of animal as the key regulators. Up to now, microRNAs have been the focus of studies on life science. In this study, we overview the latest re- search progress on microRNAs of regulation of muscle development, also introduce the identification and characterization of ani- mal miRNAs.
出处
《中国畜牧兽医》
CAS
北大核心
2014年第2期178-182,共5页
China Animal Husbandry & Veterinary Medicine
基金
国家自然科学基金(31201765)
中国农业科学院基本科研业务费(2011cj-8)
中国农业科学院科技创新工程