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Ph染色体阳性急性淋巴细胞白血病的诊治 被引量：5

Treatment of Philadelphia chromosome-positive acutelymphoblastic leukemia
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摘要 Ph染色体阳性（Ph＋）急性淋巴细胞白血病（ALL）是成人ALL的常见类型，带有标志性遗传学异常，即t（9；22）（q34；q11）染色体易位及BCR-ABL融合基因。
作者 王建祥
机构地区 中国医学科学院、北京协和医学院血液学研究所、血液病医院
出处 《中华血液学杂志》 CAS CSCD 北大核心 2014年第2期98-99,共2页 Chinese Journal of Hematology
关键词 急性淋巴细胞白血病 PH染色体阳性 BCR-ABL融合基因 诊治 遗传学异常 染色体易位 常见类型
分类号 R733.7 [医药卫生—肿瘤]
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同被引文献47

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  • 2Ravandi F,Kebriaei P.Philadelphia chromosome-positive acute lymphoblastic leukemia.Hematol Oncol Clin North Am,2009,23(5):1043-1063.
  • 3Faderl S,Kantarjian HM,Thomas D A,et al.Outcome of Philadelphia chromosome-positive adult acute lymphoblastic leukemia.Leuk lymphoma,2000,36(3-4):263-273.
  • 4Chalandon Y,Thomas X,Hayette S,et al.Is less chemotherapy detrimental in adults with Philadelphia chromosome(Ph)-positive acute lymphoblastic leukemia(ALL)treated with high-dose imatinib?Results of the prospective randomized Graaph-2005 study[C].ASH Annual Meeting Abstracts,2012,120(21):138.
  • 5Pfeifer H,Goekbuget N,Volp C,et al.Long-term outcome of 335adult patients receiving different schedules of imatinib and chemotherapy as front-line treatment for Philadelphia-positive acute lymphoblastic leukemia(Ph+ALL)[C].ASH Annual Meeting Abstracts.2010,116(21):173.
  • 6Wassmann B,Pfeifer H,Goekbuget N,et al.Alternating versus concurrent schedules of imatinib and chemotherapy as front-line therapy for Philadelphia-positive acute lymphoblastic leukemia(Ph+ALL).Blood,2006,108(5):1469-1477.
  • 7Intermesoli T,Cattaneo C,Pogliani EM,et al.In Philadelphia chromosome-positive acute lymphoblastic leukemia(Ph+ALL)imatinib(IM)and chemotherapy in combination improve remission rate,stem cell transplantation rate and long-term outcome[C].ASH Annual Meeting Abstracts,2012,120(21):662.
  • 8Ottmann OG,Wassmann B,Pfeifer H,et al.Imatinib compared with chemotherapy as front-line treatment of elderly patients with Philadelphia chromosome-positive acute lymphoblastic leukemia(Ph+ALL).Cancer,2007,109(10):2068-2076.
  • 9Mizuta S,Matsuo K,Yagasaki F,et al.Pre-transplant imatinibbased therapy improves the outcome of allogeneic hematopoietic stem cell transplantation for BCR-ABL-positive acute lymphoblastic leukemia.Leukemia,2011,25(1):41-47.
  • 10Pfeifer H,Wassmann B,Bethge WA,et al.Updated long-term results of a randomized comparison of prophylactic and pre-emptive imatinib following allogeneic stem cell transplantation for Philadelphia chromosome positive acute lymphoblastic leukemia(Ph+ALL)[C].ASH Annual Meeting Abstracts,2011,118(21):247.

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中华血液学杂志
2014年 第2期

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