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儿童肝脏巨大间叶错构瘤伴甲胎蛋白升高的诊治探讨 被引量:4

Diagnostic values of elevated alpha fetoprotein in children with hepatic mesenchymal hamartoma
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摘要 目的探讨儿童肝脏间叶错构瘤的临床特征、诊断与治疗。方法对10例肝脏间叶错构瘤患儿术前均行腹部B型超声、增强CT及血甲胎蛋白检查。6例行右半肝切除术,2例行肝左三叶切除术,2例行左外叶切除术。结果10例患儿均顺利完成手术,无并发症发生,术后7~9d痊愈出院。所有患儿随访6~48个月,腹部B型超声检查无肿瘤复发。复查AFP均正常,患儿生长发育良好。结论肝脏间叶错构瘤与肝脏恶性肿瘤有类似的临床症状和体征,常伴甲胎蛋白升高,临床上容易与肝脏恶性肿瘤混淆。外科手术是最佳治疗方法,可行肿瘤局部切除或规范性肝切除术,肿瘤完整切除后,偶有复发或恶变,需定期随访复查。 Objective To explore the clinical characteristics, diagnosis and treatment of hepatic mesenchymal hamartoma in children. Methods All cases were diagnosed with B-ultrasonography, computed tomography scan and alpha fetoprotein (AFP). All patients underwent operations of right hemihepatectomy (n = 6), left trilobectomy (n = 2) and left hemihepatectomy (n = 2). Results All operations were successful without complications. Discharge was within 7 9 days. During a follow-up period of 6-24 months, all patients achieved tumor-free survival with a normal level of AFP. Conclu- sions Hepatic mesenchymal hamartoma and hepatoblastoma have similar clinical characteristics. The first-choice treatment is either local tumor resection or hepatectomy. And long-term follow-ups are of- ten necessary.
出处 《中华小儿外科杂志》 CSCD 北大核心 2014年第2期97-99,共3页 Chinese Journal of Pediatric Surgery
关键词 儿童 肝脏 错构瘤 甲胎蛋白 外科手术 Child Liver Hamartoma Alpha-fetoproteins Surgical procedures,operative
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参考文献9

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二级参考文献22

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