摘要
目的分析铜绿假单胞茵耐药性及耐药趋势，为临床预防感染及合理用药提供依据。方法2010年1月-2012年12月临床各科室按标准方法采集送检标本，采用美国BDBBLCrystal微生物鉴定仪进行鉴定，药敏采用纸片琼脂扩散法（KB法），按美国临床实验室标准化协会（CLSI）标准执行。结果316株铜绿假单胞菌中对庆大霉素耐药率最高，为69．4％；对亚胺培南耐药率最低，为11．3％；其余被检测抗茵药物的耐药率在12．9％～50．8％之间。结论铜绿假单胞菌耐药情况日趋严重，有逐年上升的趋势。各级医院应严格贯彻抗茵药物使用管理制度，加强细菌耐药性的监测与防控。
Objective To analyze drug-resistance of Pseudomonas aeruginosa and the trend of its drug-resistance so as to provide the evidences for clinical prevention of infection and rational use of medicines. Method Specimens were collected by clinical departments with standard methods from January 2010 to December 2012 and were tested by u- sing American BD BBL Crystal microbial identification instruments, the susceptibility were detected with the IKirby- Bauer disk diffusion Method （KB method） according to the standards of American Clinical and Laboratory Standards Institute （CLSI）. Results 316 strains of Pseudomonas aeruginosa had the highest gentamicin-resistance with the rate of 69.4 % and the lowest imipenem-resistance with the rate of 11.3% and the rest resistance rates for antimicrobial drugs tested were between 12.9% and 50.8%. Conclusion The drug-resistance of Pseudomonas aeruginosa is getting worse with a increasing trend year by year. Every hospital should strictly follow the rules of antimicrobial drug use and strengthen the surveillance and control of bacterial resistance.
出处
《保健医学研究与实践》
2014年第1期52-53,共2页
Health Medicine Research and Practice
关键词
铜绿假单胞菌
耐药率
抗菌药物
Pseudomonas aeruginosa
Resistance rates
Antimicrobial drug
