摘要
测定了83例广西壮族人的线粒体DNA（mtDNA）第一高变区515bp的序列，并从这一母系遗传标记的角度对壮族人群的起源和群体的遗传结构进行了探讨。在所测定的83个个体中，共检测到66个单倍型，包括71个多态位点，显示了高度的遗传多样性。对单倍型的系统发育分析表明：壮族人群内部存在一定的分化，不同地区的壮族人群在mtDNA遗传变异上有一定的差异，其中柳州和河池地区的个体有一半以上属于聚类簇，而南宁和百色地区的个体属于聚类簇的较多。结合已相关报道的人群比较分析显示，壮族和我国北方民族群体亲缘关系较远，而与南方的少数民族及南方汉族亲缘关系较近。壮族人群中单倍型辐射群体分布频率、系统树中壮族人群与其他人群聚类先后次序都表明壮族是一个较为典型的南方群体。
The mtDNA hypervariable segment sequences (515bp) were sequenced in 83 Zhuangs from Guangxi Province, with the aim to learn more about the origin and genetic structure of the current Zhuangs. 66 haplotypes were identified in the samples, with 71 sites showing polymorphism. Phylogenetic analysis of the 66 haplotypes suggests that there are geographic differentiation in current Zhuangs, and those from the 4 geographic regions (Nanning, Hechi, Baise and Liuzhou) have different distribution frequencies in the cluster , and in the tree. More than 50% individuals from Liuzhou and Hechi converge into cluster , while those from Nanning and Baise have high frequency in cluster . Combined with the analysis of the reported data, the Zhuang ethnic group shows remote affinity to those from North China, whereas it is close to those in South China. The frequencies of the radiation groups in Zhuangs, together with the phylogenetic relationship of the Zhuang ethnic group in the tree suggest that the Zhuang is a typical south population.
基金
国家自然科学基金
中国科学院和云南省自然科学基金&&
