摘要
目的了解医院住院患者念珠菌感染动态变化及其耐药性,为有效控制念珠菌感染提供参考。方法采用回顾性调查方法,对某医院2009-2011年住院患者感染标本念珠菌检出情况进行调查,并进行药敏试验结果分析。结果调查期间该医院共送检病原学标本11 378份,检出念珠菌1 407株,分离率为12.4%。2011年与2009年相比,念珠菌分离率上升了1.9%。以深部念珠菌感染为主,下呼吸道念珠菌感染占79.9%,其中白色念珠菌感染占70.8%。临床分离的念珠菌除对两性霉素B比较敏感之外,对其他4种抗真菌药物均存在不同程度的耐药性。结论该医院住院患者感染标本念珠菌分离率呈现逐年增加趋势,白色念珠菌是感染的优势菌株,提示应重视临床念珠菌感染的防控。
Objective To understand the dynamic changes and drug resistance of Cam]ida infection of hospitalized pa-tients and to provide the reference for effective control. Methods The retrospective method and drug sensitivity test were used to survey and detect the Candiad isolates in infection specimens of the hospitalized patients in a hospital during year 2009 - 2011. Results There were 1 407 strains of Candidaisolated from 11 378 etiological specimens and the detection in-cidence of Candidas was 12.4%. Compared with the incidence over the past three years, it had increased by 1.9%. Deep Cam]ida infection was the primary, the proportion of Candida infection of lower respiratory tract was 79. 9% and the Candia albicans infection was 70. 8%. Except for the Amphotericin B, the clinical isolated Candia had different extent of re-sistance for the other four kinds of antifungal drugs. Conclusion The incidence of Candida in infection specimens of the hospitalized patients has taken on a rising trend, and the Candia albicans is the main strain of infections. It should be paid more attention to prevention and control of the clinical Candida infection.
出处
《中国消毒学杂志》
CAS
北大核心
2014年第2期134-136,共3页
Chinese Journal of Disinfection
基金
成都军区"十二五"医学科研计划项目(C12004)
关键词
念珠菌
医院感染
耐药性
监测
Candida
nosocomial infection
drug resistance
surveillance
