摘要
目的研究医院内感染鲍曼不动杆菌对抗菌药物的耐药性变迁及分布特点,为有效控制提供依据。方法通过回顾性调查方法,对北京某大型综合医院2005-2011年住院病人医院获得感染的鲍曼不动杆菌耐药情况变化规律及分布特点进行分析研究。结果该医院在7年中共诊断医院内获得感染患者4 833例,共分离到致病菌1 775株,其中鲍曼不动杆菌419株,构成比为23.6%。医院感染标本鲍曼不动杆菌分离率由2005年的20.1%上升至2009年的38.1%,从2010年始下降至2011年的22.8%。临床分离的鲍曼不动杆菌对临床常用抗菌药物的耐药率呈现逐年上升的趋势,对亚胺培南的耐药率由2005年的5%上升到2011年的87.5%。结论临床分离的鲍曼不动杆菌的耐药率总体呈上升趋势,应制定出最佳控制和治疗方案。
Objective To study resistance changes and distribution characteristics of nosocomial infections of Acineto- bacter baumannii against antimicrobial drugs, in purpose of providing basis for effective control. Method Retrospective survey was used to analyze Acinetobacter baumannii resistance variation and distribution characteristics in Beijing particular large - scale integrated hospital during the period between 2005 to 2011. Result Total 4 833 nosocomial infected patients were diagnosed in last seven years, and 1 755 strains of pathogens were isolated： 419 strains were Acinetobacter baumannii, which occupied 23.6%. Acinetobacter baumannii isolated ratio increases from 20. 1% to 38.1% in hospital infection speci- mens between year of 2005 and 2009, from year of 2010 dropped to 22. 8% in 2011. An increasing resistance trend in clin- ical isolated Acinetobacter baumannii against general antimicrobial drugs, resistance rate against Imipenem increased from 5 % in 2005 up to 2011 of 87.5 %. Conclusion An increasing resistance trend occurred in clinical isolated Acinetobacter baumannii. We should work out the most efficiency control and treatment programs.
出处
《中国消毒学杂志》
CAS
北大核心
2014年第1期42-44,共3页
Chinese Journal of Disinfection
关键词
鲍曼不动杆菌
医院感染
耐药性变迁
Acinetobacter baumannii
nosocomial infection
resistance variation
