摘要
目的探讨过氧化氢对口腔综合治疗台水路（DUWL）污染的消毒效果。方法在某市一家三甲综合医院采用单中心随机对照试验，比较20g／L过氧化氢对DUWL污染的消毒效果。在13台牙科治疗台中，选择同一种类型的12台，应答率为92．31％（12／13）。干预组和对照组由电脑生成随机数字，并采用盲法和隐匿分组开展实验（干预组，20g／L过氧化氢冲洗，6台；对照组：安慰剂冲洗，6台）。分别采样四种水样：水源水、手机水、喷枪水和漱口水。相对危险度（RR）和95％可信区间（CI）被用来评价干预效果。参照GB5749{生活饮用水卫生标准》，细菌总数不超过100cfu／ml为评判标准。结果本实验共采集36份水样（手机水、冲洗水各3份）。手机水、喷枪水和漱口水为9950．00cfu／ml（4307．00～25300．00cfu／m1）、360．00cfu／ml（149．00～1720．00cfu／m1）和4250．00cfu／ml（1850．00～11925．00cfu／m1）。本次干预研究发现，采用20g／L过氧化氢可以显著降低83％微生物污染风险（RR=0．17，95％，CI=0．06—0．47）。随访研究显示，当随访24h后，细菌总数超过100cfu／ml。结论20g／L过氧化氢溶液可以显著降低DUWL微生物污染。然而，这种效果维持时间较短，应定期监测DUWL细菌总数。
Objective To explore the disinfection effect of of 2% hydrogen peroxide for dental unit waterline contamina- tion. Methods A single - centre randomized controlled, blind clinical trial was performed in stomatology department of a large Grade III- A hospital. Twelve dental units chairs （DCUs） were responsed in this trial （response rate： 92. 31%, 12/13 ）. Randomization was carried out electronically via random seed generation, by an in - house computer programmer; therefore, participants and researchers were blinded to group allocation at randomization. The intervene group conclude six DCUs with 2% hydrogen peroxide flushing, and the control group conclude six DCUs with placebo flushing. The water sam- ple were source water, handpiece water, spray gun water and mouth wash water. Relative risk （RR） and 95% confidence in- tervals （CI） were used to evaluate the risk of the intervention. Intervention group was conducted for one week follow - up to seek the ending point （total bacterial count ≤ 100 cfu/ml） according to the standard of drinking water in China. Results Thirty six samples were available in this trial （Each DCU collected for three samples, hand -piece water, three -ways - syringe water and mouth wash, respectively）. We found out that 2% hydrogen peroxide would significantly decreased the total bacterial count compared with the placebo （RR =0. 17, 95% CI =0. 06 -0. 47）. Remarkably, total bacterial count for each sample exceeded the standard of drinking water （ 100 cfu/ml） in the 24 hours follow - up. Conclusion 2% hy- drogen peroxide significantly decreased owered the total bacterial count of water supplied for DCUs while this effects would not maintained more than 24 hours and periodical surveillance should be warranted.
出处
《中国消毒学杂志》
CAS
北大核心
2014年第1期5-8,共4页
Chinese Journal of Disinfection
基金
江苏高校优势学科建设工程资助项目(JX10231801)
江苏省卫生厅预防医学课题(Y2012046)
十二五科教兴卫工程"突发公共卫生事件应急处置创新平台"(ZX201109)
关键词
过氧化氢
细菌总数
口腔综合治疗台
hydrogen peroxide
total bacterial count
dental unit chair
