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浆细胞性乳腺炎与结核菌L型感染误诊探讨 被引量:37

Exploration of Misdiagnosis of Plasma Cell Mastitis and Infection of l-forms of Tubercle Bacillus
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摘要 目的 :探讨浆细胞性乳腺炎与结核菌 L型感染的关系 ,初步分析临床及病理误诊的可能原因。方法 :应用组织切片改良抗酸染色及牛型结核菌卡介苗抗体免疫组化染色对 5 6例病理学诊断为浆细胞性乳腺炎的病例重新切片检查。结果 :5 6例中有 2 4例 (6 0 .7% )抗酸染色检出结核菌 L型 ;41例 (73.2 % )免疫组织染色阳性。结核菌 L型主要分布于炎症灶内、肉芽组织中及乳腺导管上皮细胞和巨噬细胞内、形态多样 ,有巨形体、圆球体、原生小体等常可聚集成堆。结论 :浆细胞性乳腺炎的发生可能与结核菌 L型的感染有关或可能为乳腺结核的亚型 ,为减少误诊和漏诊应加作抗酸染色及免疫组化染色。 Objective:To explore the relations between plasma cell mastitis and the infection of l forms tubercle bacillus and initially analyze the possible causes coming from clinic and pathological misdiagnosis.Methods:56 cases diagnosed as plasma cell mastitis by general pathological examinatorial methods were re maked into slides by intensified kinyoun and anti BCG immunohistochemical staining.Results:The L Forms of tubercle bacillus were found in 34 of 56 cases(60.7%)by acid fast staining and in 41 of 56 cases(73.2%)by immunohistochemical staining.L forms of tubercle bacillus mainly exist in inflammation range,granulation tissue,mammary ductal epithelial cell and macrophage.They have all sorts of shapes,such as spheroplast and protoplast,and usually gather in groups.Conclusion:Plasma cell mastitis may be associated with the infection of L forms of tubercle bacillus or sub type of tuberculosis of the breast.To avoid the mising diagnosis and the misdiagnosis,we should make extra examinations by acid fast staining and immunohistochemicel staining.
作者 许涛 钱琛
出处 《中国误诊学杂志》 CAS 2001年第1期31-32,共2页 Chinese Journal of Misdiagnostics
关键词 乳腺炎 诊断 结核L型菌 误诊 免疫组织化学 Mastitis/diagnosis Lforms Tuberculosis/diagnosis Diagnostic errors Immunohistochemistry
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  • 1张世馥,中华病理学杂志,1993年,22卷,80页
  • 2林特夫,中华医学杂志,1983年,63卷,502页
  • 3于国,李维华,刘志遐.无反应性结核病(附5例分析)[J]实用内科杂志,1986(02).

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