摘要
目的:通过对就诊治疗的0~6岁儿童肺炎的病原学检测结果进行分析,了解呼吸道病原体在0~6岁儿童肺炎中分布情况,探讨呼吸道九联检的临床意义.方法:采集284例临床已确诊为肺炎的0~6岁儿童的血清,用间接免疫荧光法(IFA)测定四种非典型病原体:嗜肺军团1型(Legionella pneumnopila typel,LP1)、肺炎支原体(Mycoplasma pneumonia,MP)、肺炎衣原体(Chlamydia pneumonia,CPn)、Q热立克次体(Richettsia query,QFR);和五种呼吸道病毒:腺病毒(Adenovirus,ADV)、呼吸道合胞病毒(Respiratory syncytial virus,RSV)、甲型流感病毒(Influenza A virus,IFVA)、乙型流感病毒(Influenza B virus,IFVB)、副流感病毒(Parainfluenza virus,PIVs);共九种病原体的IgM抗体.结果:284例0~6岁儿童患者中,总的呼吸道病原体阳性率为38.03%,其中阳性率最高的是MP(16.2%),中等阳性率的病原体RSV(7.04%)、INFB (6.34%)、PIVs(3.52%)、ADV(2.11%)、LP1(1.76%),阳性率最小的病原体为CPn(0.35%)和QFR(0.00%).结论:呼吸道九联检可明确引起0~6岁儿童肺炎的病原体,从而为临床用药提供依据.
Objective According to analyze the detective results of the etiology of pneumonia in children aged 0 -6 to learn the distri- bution of respiratory pathogens in pneumonia of children aged 0 - 6 and discuss the clinical significance of the nine kinds tests of respiratory tract. Method 284 pipes of serum of children aged 0 -6 who had been diagnosed as pneumonia, were assayed four kinds of non - typical pathogens Legionella pneumnopila typel( LP1 ) ,Myeoplasma pneumonia(MP) Chlamydia pneumonia(CPn) Richettsia query(QFR) ] by IFA and five types of respiratory viruses:Adenovirus(ADV) ,Respiratory syncytial virus(RSV) ,Influenza A virus(IFVA) Influenza B virus(IFVB) Parainfluenza virus (PIVs). And the total number of pathogenic antibodies was nine. Results Generally speaking, among the 284 children, the positive rate was MP( 16.2% ). The middle positive rate of etiology are RSV (7.04%) ,INFB (6. 34% ) ~PIVs( 3. 52% ) ADV2. 11%) and LPI ( 1, 76%) . Moreover, the lowest positive rate of etiology were CPn (0.35%) and QFR (0.00%) o Concision Obviously, the nine kinds of tests of respiratory tract can cause the pneumonia pathogena of children aged 0 - 6 and provide tile evidence of clinical medieaion.
出处
《吉林医学》
CAS
2014年第4期722-724,共3页
Jilin Medical Journal
关键词
儿童肺炎
呼吸道九联检
病原体
临床用药
Pneumonia in children
Nine kinds of tests of respiratory tract
Pathogen
Clinical medication