摘要
目的：探讨应用高黏度骨水泥对骨质疏松椎体急性重度压缩性骨折（Severe vertebral compression fracture,SVCF）行经皮椎体成形术（Percutaneous vertebroplasty,PVP）的临床疗效.方法：收集骨质疏松椎体急性SVCF患者38例,男15例,女23例,平均年龄66.2岁.体位复位后应用高黏度骨水泥行PVP治疗,手术前后进行视觉模拟疼痛评分（VAS）、伤椎高度与后凸畸形的X线片测量.结果：38例手术均安全完成,术中骨水泥注入量平均3.0 ml,术后平均随访20.7（12～42）个月.术后 VAS评分较术前改善（P＜0.05）,椎体前缘、中线高度及后凸畸形较术前明显恢复（P＜0.05）.4例（10.5%）出现骨水泥渗漏,但无临床症状及体征.结论：应用高黏度骨水泥行PVP治疗提高手术安全性,术前结合体位复位是治疗骨质疏松椎体急性SVCF的可行及有效的方法.
Objective To evaluate the clinical efficacy of percutaneous vertebroplasty（PVP） with high viscosity bone cement in treating severe osteoporotic vertebral compression fractures（SVCF）. Method Thirty - eight patients with SVCF were treated by postural reduction and PVP with high viscosity bone cement,including 15 males and 23 females with an average age of 66.2 years. Pain relief, restoration of vertebral height and kyphosis＇eorrection were evaluated by comparison before and after operation using visual analogue scale（ VAS）, radio- graphy. Results All 38 eases underwent operation successfully with average injected bone cement 3. 0 ml. The mean time of follow - up was 20.7 months（ 12 -42 months）. The patients＇VAS scores were significantly improved after operation（ P 〈 0. 05 ）. The height restoration of vertebral anterior border and midline and the correction of kyphosis were significantly improved（ P 〈 0. 05 ）. Cement leakage was found in 4 eases（ 10. 5% ） without any clinical symptoms and signs. Conclusion The high viscosity bone cement can be employed more safely during PVP. PVP with high viscosity bone cement and postural reduction are effective and relatively safe for the treating acute SVCF.
出处
《吉林医学》
CAS
2014年第4期705-707,共3页
Jilin Medical Journal
基金
永川区科委软科学研究计划项目[项目编号:YCSTC
2012BE5006]
重庆医科大学第五临床学院院级项目[项目编号:YJYB2011014]
关键词
骨质疏松
椎体重度压缩性骨折
经皮椎体成形术
高黏度骨水泥
Osteoporosis
Severe vertebral compression fracture
Percutaneous vertebroplasty
High viscosity bone cement
