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湿润烧伤膏与碱性成纤维细胞生长因子治疗小儿烧伤创面的疗效对比 被引量:5

Comparison of Curative Effect of Moist Exposed Burn Ointment(MEBO)and Basic Fibroblast Growth Factor(rb-bFGF) on Pediatric Burn Wounds
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摘要 目的 探索促进小儿深Ⅱ度烧伤创面愈合的有效、可靠、易于推广的治疗方法.方法 将60例患儿分为试验组(30例)与对照组(30例).试验组:患儿创面外用湿润烧伤膏(MEBO),单层油纱覆盖,每天换药1次;对照组:患儿创面外用碱性成纤维细胞生长因子(rb-bFGF),单层油纱覆盖,每天换药1次,对比观察两组患儿创面愈合情况.结果 试验组患儿创面坏死组织液化早、脱落快,治疗1周后仅有4例患儿创面培养带菌,创面愈合时间为2~3周,4例患儿创面愈后有色素沉着,无瘢痕增生,与对照组相比,差异均具有明显的统计学意义.结论 湿润烧伤膏治疗小儿烧伤创面的疗效优于rb-bFGF,是一种治疗烧伤创面的有效药物,且痛苦小、费用低,容易被患儿及家属接受,易于推广. Objective To explore an effective, reliable and easy-tu-popularize therapy of deep second degree pediatrie burn wounds. Methods Sixty burned children in hospital were randomly divided into two groups, 30 cases in each group. Experimental group was treated with Moist Exposect Burn Ointment (MEBO) ; control group was treated with haste fibrohlast gruwth factor (rb-hFGF). All wounds were covered by single-layer oil gauze and dressing change was conductedonce a day. Wound healing status was comparatively observed in two groups. Results Earlier liquetaction aml exfoliation of necrotic tissues at wound sites were found in experimental group, in which germs were fi)uml in euhure of wound neerotie tissue uf only four eases after 1 week treatment, wuunds healed within 2 -3 weeks, and fimr cases had pigmentation without sear hyperplasia after healing, which had statistical significance eompared with that of eontrol group. Conclusion Moist Exposed Burn Ointment (MEBO) is superior to rh-hFGF in the treatment of pediatric burn wounds. Treatment with M EBO has better efficacy, less suffering and lower eust, thus it is easily accepted hy patients and their guardians and popularized in clinical application.
出处 《中国烧伤创疡杂志》 2014年第1期26-29,共4页 The Chinese Journal of Burns Wounds & Surface Ulcers
关键词 湿润烧伤膏 碱性成纤维细胞生长因子 小儿烧伤 深Ⅱ度烧伤 疗效对比 Muist Exposed Burn OintmenT (MEBO) Basic Fibrohlast Growth Factor Pediatric burn deep II degree burn Efficacy eumparison
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