摘要
青光眼是眼科常见的不可逆性致盲眼病，其主要损害是视网膜神经节细胞（RGCs）及其轴突的变性和丢失，最终可导致视野损害和视力下降。视野检查是青光眼早期诊断以及随访过程中观察病情进展最重要的视功能检查方法，但由于视野检查存在较强的主观性，因此如何建立客观、规范的视野评价和分析方法一直受到青光眼学者们的关注。就目前临床及研究中常用的视野缺损分级方法，包括视野指数、青光眼半视野检测（GHT）、晚期青光眼干预研究（AGIS）评分法、早期青光眼试验（EMGT）评分法、多中心青光眼初始治疗研究（CIGTS）评分法等，及其优缺点进行综述，希望能够对临床及科学研究中视野评价方法的选择有所帮助。
Glaucoma is a common eye disease which may cause irreversible blindness. This ocular degenerative disease affects retinal ganglion cells （RGCs） and eventually causes optic nerve dysfunction by way of axonal loss. Patients with glaucoma may show characteristic changes of optic disc, damages of visual field and impairment of vision. Detection and evaluation of the impairment of visual field in patients with glaucoma are essential for the diagnosis and estimation of progression of this disease. Numerous techniques have been developed to detect field progression, but no standard has been widely accepted. Assessment Methods including visual field indices, glaucoma hemifield test （GHT） , Advanced Glaucoma Intervention Study （AGIS） , Early Manifest Glaucoma Trial （EMGT） ,Collaborative Initial Glaucoma Treatment Study （CIGTS）, as well as the strength and limitation of each method were reviewed in this article in order to find out suitable ways to evaluate visual field defects in patients with glaucoma in clinical works and researches.
出处
《中华实验眼科杂志》
CAS
CSCD
北大核心
2014年第2期187-192,共6页
Chinese Journal Of Experimental Ophthalmology
关键词
青光眼
视野缺损
评价方法
Glaucoma
Visual field defect
Assessment
