摘要
目的 评估新型光学低相干反射仪Lenstar、Pentacam眼前节综合分析系统和眼前节生物测量仪Sirius测量白内障患者中央角膜厚度（CCT）、前房深度（ACD）、角膜曲率（Km）的差异性与一致性,为临床使用提供依据.方法 前瞻性对照研究.同一观测者分别应用Lenstar 、Pentacam和Sirius 测量40例（40眼）白内障患者的CCT、角膜内皮到晶状体前表面的ACD （ACDendo）、角膜上皮到晶状体前表面的ACD（ACDepi）和Km,眼别的选择采用随机方式.对3种仪器测量的以上指标比较采用重复测量方差分析,进一步用Bonferroni法两两比较仪器间的差异,一致性比较采用Bland-Altman统计分析法.结果 Lenstar、Pentacam和Sirius测量CCT的平均值分别为（528.18＆#177;29.12）μm、（533.21＆#177;27.02）μm和（534.48＆#177;26.15） μm,ACDendo分别为（2.54＆#177;0.41）mm、（2.54＆#177;0.43）mm和（2.57＆#177;0.43）mm,ACDepi分别为（3.07＆#177;0.41）mm、（3.08 ＆#177;0.42） mm和（3.10＆#177;0.43）mm,差异均有统计学意义（F=11.641、9.961、12.539,P＜0.01）,Km值分别为（44.05＆#177;1.69）D、（43.99＆#177;1.65）D、（43.93＆#177;1.63）D,差异有统计学意义（F=4.186,P＜0.05）.3种仪器测量CCT、ACDendo、ACDepi、Km的95％一致性区间（LoA）较小,其上下限最大的绝对值分别为26.41 μm、0.12 mm、0.12 mm和0.61 D,一致性好.结论 Lenstar、Pentacam和Sirius测量白内障患者中央角膜厚度、前房深度、角膜曲率具有良好的一致性,为临床白内障患者眼前节参数的测量提供了新的选择.
Objective To assess the differences and agreements among measurements of cataractous eyes using Lenstar LS900 biometer,Pentacam rotating Scheimpflug photography and a Sirius Scheimpflug-Placido disc topographer.The following measurements were taken：central corneal thickness （CCT）,anterior chamber depth from the corneal endothelium to the anterior lens capsule （ACDendo）,anterior chamber depth from the corneal epithelium to the anterior lens capsule （ACDepi） and mean keratometry （Kin）.Methods In this prospective clinical study,CCT,ACD （including ACDendo and ACDepi） and the Km of 40 eyes were randomly obtained by Lenstar,Pentacam and Sirius.All measurements included the 3 methods which were compared using a repeated-measures analysis of variance （ANOVA）,with a Bonferroni multiple comparison correction.Bland-Altman analyses were used to evaluate the agreement between the devices.Results The mean CCTs obtained by Lenstar,Pentacam and Sirius were 528.18＆#177;29.12 μm,533.21＆#177;27.02 μm and 534.48＆#177;26.15 μm,respectively.The mean ACDendo obtained by Lenstar,Pentacam and Sirius were 2.54＆#177;0.41 mm,2.54＆#177;0.43 mm and 2.57＆#177;0.43 mm,respectively.The mean ACDepi obtained by Lenstar,Pentacam and Sirius were 3.07＆#177;0.41 mm,3.08＆#177;0.42 mm and 3.10＆#177;0.43 mm,respectively.The mean Km obtained by Lenstar,Pentacam and Sirius were 44.05＆#177;1.69 D,43.99＆#177;1.65 D and 43.93＆#177;1.63 D,respectively.There were significant differences among the results of these three methods in CCT （F=11.641,P〈0.01）,ACDendo （F=9.961,P〈0.01）,ACDepi （F=12.539,P〈0.01）,and Km （F=4.186,P〈0.05）.The Bland-Altman plot analyses showed that the three devices had comparable results for CCT,ACD and Km.For the maximum absolute values of 95% limits of agreement （LoA） were 26.41 μm,0.12 mm,0.12 mm and 0.61 D respectively.Conclusion Lenstar,Pentacam and Sirius demonstrated high agreement for CCT,ACD and corneal curvature measurements in cataractous eyes.
出处
《中华眼视光学与视觉科学杂志》
CAS
2014年第1期30-35,共6页
Chinese Journal Of Optometry Ophthalmology And Visual Science
基金
浙江省医药卫生科技计划项目，浙江省教育厅科研项目，温州市科技局资助项目
关键词
中央角膜厚度
前房深度
角膜曲率
一致性
Lenstar
Pentacam
Sirius
Lenstar
Pentacam
Sirius
Central corneal thickness
Anterior chamber depth
Corneal curvature
Agreement
