期刊文献+

血培养阳性标本病原菌分布及耐药特征 被引量:6

原文传递
导出
摘要 目的了解本院血培养阳性标本的病原菌临床分布及耐药性。方法对2009年6月—2012年6月本院临床送检的血液标本1 830份进行培养,分析病原菌检出情况、分布特征及对常用抗生素的耐药情况。结果共分离出病原菌624株,检出率居前4位的病原菌依次为凝固酶阴性葡萄球菌220株(35.3%),金黄色葡萄球菌72株(11.5%),大肠埃希氏菌66株(10.6%),白色假丝酵母菌17株(2.7%);儿科、血液科、呼吸科及感染科检出病原菌以凝固酶阴性葡萄球菌为主,老年病科金黄色葡萄球菌多见,消化科和泌尿外科以大肠埃希氏菌为主,综合ICU和骨科白色假丝酵母菌多见;葡萄球菌对青霉素、苯唑青霉素高度耐药,未发现耐万古霉素菌株;革兰阴性菌对头孢类抗生素的耐药率>50%,铜绿假单胞菌和鲍曼不动杆菌对亚胺培南和头孢哌酮+舒巴坦钠的耐药率<10%。结论本院血培养中病原菌以凝固酶阴性葡萄球菌为主,且耐药情况较严重,临床医生应根据病原菌的药物敏感结果合理用药。
出处 《中华实用诊断与治疗杂志》 2014年第2期207-208,共2页 Journal of Chinese Practical Diagnosis and Therapy
  • 相关文献

参考文献6

二级参考文献39

  • 1文细毛,任南,吴安华,徐秀华.老年患者医院内菌血症病原菌分布与相关因素分析[J].中国现代医学杂志,2004,14(17):130-133. 被引量:5
  • 2李素英,周树丽,王玫.临床细菌耐药性监测及干预策略探讨[J].中华医院感染学杂志,2004,14(1):77-79. 被引量:27
  • 3李华,马筱玲.临床分离大肠埃希菌耐药性检测[J].安徽医学,2007,28(1):72-73. 被引量:9
  • 4Gemmell CG.Susceptibility of a variety of clinical isolates to linezolid:a European inter-country comparison[J].J Antimicrob Chemother,2001,48(1):47-52.
  • 5倪语星.2005年中国CHINET铜绿假单胞菌耐药性分析[J].中国感染与化疗杂志,2007,7(4):274-278. 被引量:49
  • 6Horii T, Suzuki Y, Monji A, et al. Detection of mutations in quinolone resistance-determining regions in levofloxacin- and methicillin-resistant Staphylococcus aureus: effects of the mu-tations on fluoroquinolone MICs [J]. Diagn Microbiol Infect Dis, 2003,46(2) : 139-145.
  • 7National Committee for Clinical Laboratory Standards. Perfor-mance standards for antimicrobial disk susceptibility tests[S].6th ed. Approved standard M2 A6 (M100-S7). Wayne:NCCLS, 2002.
  • 8Eveillard M, Schmit JL, Eb F. Antimicrobial use prior to the acquisition of multiresistant bacteria[J]. Infect Control Hosp Epidemiol, 2002,23(3) : 155-158.
  • 9Bourbeau PP, Pohlman JK. Three days of incubation may be sufficient for routine blood cultures with BacT/Alert FAN blood culture bottles. J Clin Microbiol,2001,39 :2079-2082.
  • 10McGowan K L, Foster J A, Coffin SE. Outpatient pediatric blood cultures : Time to positivity. Pediatrics,2000,106:251-255.

共引文献117

同被引文献36

  • 1李介华,袁春雷,温伟洪.不同病区和标本来源金黄色葡萄球菌感染的耐药性监测[J].现代预防医学,2006,33(10):1946-1949. 被引量:5
  • 2周庭银,倪语星,王明贵.血流感染实验诊断与临床诊治[M].上海:上海科学技术出版社,2011:41_42.108—109.120—121.
  • 3李兰娟,任红.传染病学[M].8版.北京:人民卫生出版社,2013:428.
  • 4Yanai M, Uehara Y, Yagoshi M, et al. Interpretation of the results of blood culture and interventional role by clinical laboratory physicians [J]. Rinsho Byori, 2006,54(10) : 1059-1065.
  • 5Healy CM,Baker CJ, Palazzi DL, et al. Distinguishing true coagulase-negative Staphylococcus infections form contaminants in the neonatal intensive care unit [J]. J Perinatolm, 2013,33(1) .. 52-58.
  • 6Chen Y, Zhang W, Knabel SJ. Multi-virulence-locus sequence typing identifies single nucleotide polymor- phisms which differentiate epidemic clones and out- break strains of Listeria monoeytogenesEJ]. Clin Mi- crobiol, 2007,45 (3) : 835-846.
  • 7Sievert DM, Boulton ML, Stoltrnan G, et al. Stapbylomccus anreus resistant to vancomyc in United State, 2002[J]. MMWR Morb Mortal Weekly Rep,2002,51(26) : 565-567.
  • 8Jang HC, Choi SM, Jang MO, et al. In appropriateness ofquinolone in scrub typhus treatment due to gyrA mutation in Orientia tsutsugamushi Boryong strain[J]. J Korean Med Sci, 2013,28(5) :667-671.
  • 9Phimda K, Hoontrakul S, Suttinont C, et al. Doxycycline versus azithromycin for treatment of leptospirosis and scrub typhus[J]. Antimierob Agents Chemother, 2007,51 (9) : 3259 3263.
  • 10Tsai CC, Lay CJ, Ho YH, et al. Intravenous minocycline versus oral doxycycline for the treatment of noncomplicated scrub typhus[J].J Microbiol Immunol Infect, 2011,44 ( 1 ) : 33 38.

引证文献6

二级引证文献32

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部