摘要
目的 :通过离体实验观察人肠内菌对龙胆苦甙的代谢。方法 :采用人新鲜粪便厌氧培养 ,HPL C法定量测定代谢产物。结果 :龙胆苦甙经人肠内菌代谢生成龙胆碱和龙胆醛等主要产物。结论 :龙胆苦甙易被人肠内菌代谢 ,其代谢模式可能为龙胆苦甙→龙胆碱→龙胆醛。
The metabolism of gentiopicroside by vitro anaerobic culture with human intestinal bacteria were studied. The results showed that 1. the main metabolites were gentianine and gentianal, both are nitrogen containing compounds; 2. The mode of metabolism of gentiopicroside is gentiopicroside→gentianine→gentianal.
出处
《时珍国医国药》
CAS
CSCD
2001年第1期1-2,共2页
Lishizhen Medicine and Materia Medica Research
基金
国家“九五”攻关基金资助课题(No.969030203)
