摘要
目的 探讨颅内感染 (ICI)患者脑膜刺激征 (MIS)阴性的相关因素及其机理和临床意义。方法对 40 9例确诊的ICI患者MIS检出状况及相关临床资料进行回顾性分析。结果 本组病例的MIS阴性率为14 9% (6 1/4 0 9)。MIS阴性率 :脑实质病变组较脑膜病变组高 (P <0 .0 1) ;意识障碍组较清醒组高 (P <0 .0 1) ;病理征阳性组较病理征阴性组高 (P <0 .0 1) ;首诊时间 <2天组较 >2天组高 (P <0 .0 5 ) ;儿童及老年组较青壮年组高 (P <0 .0 5 ) ;查体者资历 <5年组较 >5年组高 (P <0 .0 5 )和非神经科专业组较神经科专业组高(P <0 .0 5 )。结论 病变部位、意识状态的不同以及有无病理征为影响ICI患者MIS检出的非常重要的相关因素 ;患者的首诊时间及年龄、医生的资历和专业的差异也是重要的相关因素。
Objective To explore the associated factors, its mechanism and clinical significance of negative meningeal irritation sign (MIS) in patients with the intracranial infection (ICI).Methods The clinical data of 409 cases with diagnosed ICI were analyzed retrospectively.Results The negative rate of MIS of 409 patients was 14.9 percent (61 of 409). The negative rate of MIS was remarkably higher in the brain parenchyma lesion group than in the meningeal lesion group ( P < 0.01 ), in the consciousness disorder group than in the no consciousness disorder group ( P < 0.01 ), in the positive pathological sign group than in the negative group ( P < 0.01 ), in the time of initially seeing a doctor <2 days group than in >2 days group ( P < 0.05 ), in the children and old group than in adult group ( P < 0.05 ), in the service time of physical examiner <5 years group than in >5 years group ( P < 0.05 ),and in the speciality of non neurology group than in the neurology group ( P < 0.05 ).Conclusion The most important associated factors for affecting MIS were the lesion locations, the consciousness conditions and the pathological signs. The important associated factors were also involved in the time of initial seeing a doctor, the age of patients, the service time and speciality of doctors.
出处
《卒中与神经疾病》
2001年第1期38-40,共3页
Stroke and Nervous Diseases
关键词
颅内感染
脑膜刺激征
相关因素
病理
Intracranial infection Meningeal irritation sign Associated factor
