摘要
目的 研究大鼠脑胶质瘤模型的MRI表现。方法 经病理和免疫组织化学染色证实的大鼠脑胶质瘤 2 0例 ,分析其MRI表现。结果 大鼠脑胶质瘤在T1WI上呈等信号。T2 WI上呈高信号 ,边界较清楚。术后第 16天时 10只大鼠出现较轻的占位效应 ,术后第 2 5天时 2 0只大鼠均出现明显的占位效应。增强扫描 :2 0只大鼠出现肿瘤呈环状强化。结论 0 5TMR -T2 WI和结合用Gd -DTPA行增强扫描能清楚显示大鼠脑胶质瘤。
Objective To investigate MRI presentation of rat brain-glioma model.Methods The MRI findings of 20 rats with brain-glioma was analyzed.The diagnosis was confirmed by pathology and immunohistochemistry.Results The rat brain-glioma showed iso-signal intensity on T 1WI and hyperintensity with well defined margin on T 2WI mild and marked mass effect are noted in 10 rats and 20 rats at the 16 th and 25 th day respectively after implantation. There was a circle enhancement in 20 rats with contrast enhoncement.Conclusion The rat brain-glioma could be best detected on MR-T 2WI and with contrast enhancement.
出处
《卒中与神经疾病》
2001年第1期32-34,共3页
Stroke and Nervous Diseases