摘要
目的 探讨原发性胆汁性肝硬化（PBC）与乙肝肝硬化（HBV-C）的失代偿期的临床特点、诊断与鉴别诊断要点、治疗重点等.方法 对2004年1月至2011年8月确诊的失代偿期PBC患者16例作回顾性分析,并随机选择此时段内16例失代偿期HBV-C患者比较分析其临床表现、生化指标、影像学检查、治疗方法和治疗效果等.结果 失代偿期PBC组以GLB、ALP、GGT及D-BIL升高明显,发生胆汁淤积较失代偿期HBV-C组明显.失代偿期PBC组红细胞、血红蛋白下降较失代偿期HBV-C组明显.失代偿期HBV-C组白蛋白下降更明显、PT延长更明显、PLT下降更明显.失代偿期PBC组自身免疫性指标常阳性.结论 失代偿期的原发性PBC治疗应该以激素为主,失代偿期的HBV-C患者治疗仍然应该以抗病毒为主.失代偿期的HBV-C的预后略好于PBC.
Objective To analyze and study the features and key points of clinical diagnosis and therapy for primary biliary cirrhosis and hepatitis B cirrhosis in decompensation period.Methods The clinical manifestation,laboratory examination,iconography examination and therapeutic schedule,treatment effectiveness were analyzed by retrospective research method in 32 patients for the past 7.5 years.Results The GLB,ALP,GGT,D-BIL were increased,autoimmunity markers were positive in primary biliary cirrhosis patients in decompensation period.The ALP and PLT were decreased,PT was increased in hepatitis B cirrhosis patients.Conclusion The hormone therapy is important for primary biliary cirrhosis patients.The antivirus therapy is important for hepatitis B cirrhosis patients.The prognosis is better for hepatitis B cirrhosis than for primary biliary cirrhosis patients in decompensation period.
出处
《国际医药卫生导报》
2014年第3期329-331,共3页
International Medicine and Health Guidance News
关键词
原发性胆汁性肝硬化
乙肝肝硬化
失代偿期
诊断
治疗
Primary biliary cirrhosis
Hepatitis B cirrhosis
Decompensation
Diagnosis
Therapy
