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沐舒坦联合固尔苏对新生儿呼吸窘迫综合征的临床疗效 被引量:5

Effect of ambroxol combined with curosurf in treatment of neonatal respiratory distress syndrome
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摘要 目的探讨沐舒坦联合固尔苏对新生儿呼吸窘迫综合征的临床疗效。方法将168例新生儿呼吸窘迫综合征患者分为观察组和对照组,观察组给予沐舒坦联合固尔苏治疗,对照组仅给予固尔苏治疗,观察两组患者治疗24 h后疗效,治疗后12 h、24 h、48 h血气指标及两组患者症状缓解时间、吸氧时间和住院时间。结果两组患者治疗24h后有效率分别为71.4%、39.3%;观察组患者治疗24 h、48 h后PaO2均明显大于对照组,而PaCO2均明显小于对照组,两组比较具有显著性差异(P<0.05);观察组患者症状缓解时间、吸氧时间以及住院时间均明显短于对照组(P<0.05)。结论沐舒坦联合固尔苏治疗可以明显改善新生儿呼吸窘迫综合征患者的血气指标,缓解症状,效果好于单用固尔苏治疗。 Objective To investigate the the clinical curative effect on neonatal respiratory distress syndrome by ambroxol and curosurf together. Methods A total of 168 cases of neonatal respiratory distress syndrome were divided into the observation group and the control group, the observation group was given ambroxol and curosurf treatment, while the control group was treated only with curosurf treatment, curative effect after treatment of 24 h, 12 h, 24 h, 48 h blood gas index and two groups of patients symptoms time, oxygen time and the hospitalization time were observed. Results The efficiency treated after 24 h of two groups were 71.4%,39.3%; Pa02 of the observation group treated after 24 h, 48 h were significantly higher than the control group, while PaC02 was significantly lower than that of the control group, with significant difference (P〈0.05), the symptoms time, oxygen time and hospital time of the observation group patients was significantly less than that of the control group (P〈0.05). Conclusion Ambroxol and curosurf treatment can obviously improve the blood gas indexes in patients with neonatal respiratory distress syndrome, having a good effect than single using of curosurf.
作者 郭倩
出处 《中国现代医生》 2014年第2期39-40,44,共3页 China Modern Doctor
关键词 沐舒坦 固尔苏 新生儿呼吸窘迫综合征 Ambroxol Curosurf Neonatal respiratory distress syndrome
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