摘要
目的探讨四联疗法治疗难治性消化溃疡患者的临床疗效及预后。方法选择难治性消化溃疡患者64例均分为两组,研究组难治性消化溃疡患者采用四联疗法进行临床治疗,对照组难治性消化溃疡患者进行三联疗法治疗。观察并记录两组患者治疗效果及不良反应发生率,并对其进行1年有效随访,记录其病情复发情况,进行统计分析。结果研究组患者经治疗后临床总有效率为84.38%,显著高于对照组患者临床治疗总有效率65.63%;研究组患者治疗过程中不良反应发生率为9.38%、随访复发率为15.63%,显著低于对照组患者不良反应发生率28.13%、随访复发率53.13%。两组比较差异具有统计学意义(P<0.05)。结论难治性消化溃疡患者应用四联疗法进行治疗可达到满意临床疗效,且不良反应发生率及复发率均较低,可有效保障患者生活质量及生命安全,值得临床推广应用。
Objective To investigate the quadruple therapy in patients with refractory peptic ulcer clinical efficacy and prognosis, such as improving patient outcomes and quality of life provide a reliable basis. Methods The study group patients with refractory peptic ulcers quadruple therapy for clinical treatment;control group patients with refractory peptic ulcer triple therapy. The two groups were observed and recorded patient outcomes and incidence of adverse reactions, and its valid for one year follow-up, record their relapse situation to allow statistical analysis, draw conclusions. Results The study group patients after treatment clinical total efifciency up to 84.38%, which was signiifcantly higher in patients with clinical total effective rate 65.63%;study group of patients during the treatment of adverse reactions was 9.38%, up 15.63 percent recurrence rate, signiifcantly lower than the control group incidence of adverse reactions in patients with 28.13%, up 53.13 percent recurrence rate, the two groups were compared statistically signiifcant results（P〈0.05）. Conclusion The patients with refractory peptic ulcers quadruple therapy for treatment can achieve satisfactory clinical efifcacy and incidence of adverse reactions and the recurrence rate is low, can effectively protect the quality of life of patients and life safety, worthy of clinical application .
出处
《当代医学》
2014年第4期84-85,共2页
Contemporary Medicine
关键词
难治性消化溃疡
四联疗法
疗效
预后
Refractory peptic ulcers
Quadruple therapy
Efifcacy
Prognosis
