摘要
目的了解妊娠期高血压疾病（hypertensivedisordercomplicatingpregnancy，HDCP）对出生结局的危害，探讨HDCP的危险因素，为防制HDCP、降低不良出生结局提供一定的理论依据。方法采用统一设计的问卷，由调查员在分娩期间对孕妇进行面对面调查，主要调查孕期生活行为、疾病、用药及膳食摄入情况，孕妇一般情况、生育史、家族史及疾病史等；并收集新生儿出生结局。结果共收集1967例合格孕妇，发生HDCP164例（8．34％）。HDCP组出生缺陷（3．09％）、早产（42．24％）、低出生体重（44．03％）、小于胎龄儿（34．88％）的发生比例明显高于对照组（分别为0．83％、5．45％、4．87％和5．34％）（x2=7．47、257．82、295．56和137．95，均有P〈0．01）。文化程度、家庭人均月收入、孕前体质指数、高血压家族史和妊娠期高血压疾病史是HDCP的独立危险因素（OR介于2．00—6．39）。结论文化程度低、家庭经济状况差、孕前超重／肥胖、有高血压家族史和妊娠期高血压疾病史是妊娠期高血压疾病的危险因素，有妊娠期高血压疾病者发生出生缺陷、早产、低出生体重和小于胎龄儿等不良出生结局的危险性高。
Objective To understand the impact of hypertensive disorder complicating pregnancy （HDCP） on birth outcomes and to study the potential risk factors for HDCP. Methods In-person interview was conducted to collect in- formation on demographic factors, lifestyle, medical conditions and medication use, dietary intake before and during preg- nancy, family history, and reproductive history. Birth outcomes were abstracted from medical records. Results Among the 1 967 study subjects, HDCP accounted for 8. 34%. The rates of birth defects, preterm births, low birth weight, and small for gestational age in women with HDCP were 3.09%, 42. 24% , 44. 03% , and 34. 88% respectively, which were significantly higher than those in women without HDCP（0. 83% ,5.45% ,4. 87% , and 5.34% respectively） （x2 = 7.47, 257. 82,295. 56 and 137. 95 ,P 〈0. 01 ）. Multivariate Logistic regression analysis showed that education, family income, body mass index before pregnancy, family history of hypertension, and history of HDCP were risk factors （ OR was between 2. 00 and 6. 39）. Conclusions Low education and family income, overweight or obesity before pregnancy, having family history of hypertension, a history of HDCP were risk factors for HDCP. HDCP was associated with noor birth outeomeg
出处
《中华疾病控制杂志》
CAS
北大核心
2014年第2期131-134,共4页
Chinese Journal of Disease Control & Prevention
基金
山西省青年科技研究基金(2013021033-2)
山西省百人计划人才项目
关键词
高血压
妊娠并发症
心血管
妊娠结局
Hypertension
Pregnancy complications, cardiovascular
Pregnancy outcome
