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卡孕栓与催产素联合或单独使用预防产后出血的临床研究 被引量:40

Clinical study on carprost joint or separate with oxytocin to prevent postpartum hemorrhage
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摘要 目的观察卡孕栓联合催产素或单独使用对产后出血的预防效果。方法将300例足月妊娠产妇随机分为3组,A组于胎儿娩出后给予催产素肌注,B组给予卡孕栓舌下含服,C组给予卡孕栓舌下含服联合催产素肌注,记录三组产后2 h、24 h出血量及产后出血率。结果 C组产后出血率低于A、B组(P<0.05);三组不良反应发生率比较差异无统计学意义(P>0.05);C组产后2 h、24 h出血量均少于A、B组(P<0.05);C组第三产程时间短于A、B组(P<0.05)。结论卡孕栓联合催产素预防产后出血效果优于单独用药,联合用药可有效缩短第三产程,降低产后出血率,改善母婴预后。 Objective To observe the effect of carprost joint or separate With oxytocin in the prevention of postpartum hemorrhage. Methods 300 cases of full-term pregnancy women were randomly divided into three groups, group A was given oxytocin intramuscularly, group B was given carprost inserted into the rectum, group C was given carprost inserted into the rectum combined with oxytocin intramuscularly ,postpartum 2 h ,24 h bleeding of three groups were recorded. Results Postpartum hemorrhage of group C was lower than that of group A and group B ( P 〈 0. 05 ) ; the incidence of adverse reactions of three groups had no significant difference ( P 〉 0. 05 ) ; postpartum 2 h ,24 h bleed- ing volume of group C were less than that in group A and group B ( P 〈 0. 05 ) ; third stage of labor of group C was shorter than that in group A and group B ( P 〈 0. 05 ). Condusion Carprost joint oxytocin to prevent postpartum hem- orrhage is better than monotherapy, combination therapy can effectively shorten the third stage of labor, reduce postpar- tum hemorrhage rate, improve maternal and child outcomes.
出处 《实用药物与临床》 CAS 2014年第1期106-108,共3页 Practical Pharmacy and Clinical Remedies
关键词 产后出血 卡孕栓 催产素 第三产程 预防 Postpartum hemorrhage Carprost Oxytocin Third stage of labor Prevention
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